Dynamic compression of the cerebral vasculature induced by changes of pleural pressure during mechanical ventilation

Michael L. Daley, Han Sulhyung, Michael A. Meledeo, Richard L. Pasley, Charles Leffler

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Previously, we have reported that during normal tone the intracranial pressure (ICP) and arterial blood pressure (ABP) recordings are not similar and as the cerebrovasculature dilates the corresponding ICP and ABP recordings become progressively similar. Furthermore, estimates of pial venous blood flow reveal that flow during the expiration phase of ventilation was found to be uniformly higher than flow during inhalation flow for all states of vascular dilation. The purpose of this study was to develop a preliminary test of the premise that cyclic compression of the cerebral capillary bed and venules occurs during positive pressure ventilation and it causes the corresponding cyclic variation of the ICP baseline recording during normal tone. Furthermore, this cyclic compressional effect progressively reduces as tone is lost and correspondingly the cyclic variation of the ICP baseline recording becomes diminished As a result the ICP recording becomes strongly correlated with the ABP recording. Preliminary analysis of pial venous blood flow characteristics and measures of anatomical changes of the pial vasculature during ventilation support our premise.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PublisherIEEE
Number of pages1
Volume1
ISBN (Print)0780356756
StatePublished - Dec 1 1999
Externally publishedYes
EventProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA
Duration: Oct 13 1999Oct 16 1999

Other

OtherProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
CityAtlanta, GA, USA
Period10/13/9910/16/99

Fingerprint

Blood pressure
Intracranial Pressure
Artificial Respiration
Ventilation
Pressure
Blood
Arterial Pressure
Venules
Positive-Pressure Respiration
Inhalation
Blood Vessels
Dilatation

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Daley, M. L., Sulhyung, H., Meledeo, M. A., Pasley, R. L., & Leffler, C. (1999). Dynamic compression of the cerebral vasculature induced by changes of pleural pressure during mechanical ventilation. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 1). IEEE.

Dynamic compression of the cerebral vasculature induced by changes of pleural pressure during mechanical ventilation. / Daley, Michael L.; Sulhyung, Han; Meledeo, Michael A.; Pasley, Richard L.; Leffler, Charles.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 1 IEEE, 1999.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Daley, ML, Sulhyung, H, Meledeo, MA, Pasley, RL & Leffler, C 1999, Dynamic compression of the cerebral vasculature induced by changes of pleural pressure during mechanical ventilation. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 1, IEEE, Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS), Atlanta, GA, USA, 10/13/99.
Daley ML, Sulhyung H, Meledeo MA, Pasley RL, Leffler C. Dynamic compression of the cerebral vasculature induced by changes of pleural pressure during mechanical ventilation. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 1. IEEE. 1999
Daley, Michael L. ; Sulhyung, Han ; Meledeo, Michael A. ; Pasley, Richard L. ; Leffler, Charles. / Dynamic compression of the cerebral vasculature induced by changes of pleural pressure during mechanical ventilation. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 1 IEEE, 1999.
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