Dynamic task-specific brain network connectivity in children with severe reading difficulties

Michael Vourkas, Sifis Micheloyannis, Panagiotis G. Simos, Roozbeh Rezaie, Jack M. Fletcher, Paul T. Cirino, Andrew Papanicolaou

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

We investigated patterns of sensor-level functional connectivity derived from single-trial whole-head magnetoencephalography data during a pseudoword reading and a letter-sound naming task in children with reading difficulties (RD) and children with no reading impairments (NI). The Phase Lag Index (PLI), a linear and nonlinear estimator, computed for each pair of sensors, was used to construct graphs and obtain estimates of local and global network efficiency according to graph theory. In the 8-13. Hz (alpha band) and 20-30. Hz (gamma band) range, RD students showed significantly lower global efficiency than NI children, for the entire MEG recording epoch. RD students also displayed reduced local network efficiency in the alpha band. Correlations between phonological decoding ability and graph metrics were particularly evident during the task that posed significant demands for phonological decoding, and followed distinct time courses depending on signal frequency. Results are consistent with the notion of task-dependent, aberrant long- and short-range functional connectivity in RD children.

Original languageEnglish (US)
Pages (from-to)123-128
Number of pages6
JournalNeuroscience Letters
Volume488
Issue number2
DOIs
StatePublished - Jan 20 2011

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Reading
Brain
Students
Magnetoencephalography
Head

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Vourkas, M., Micheloyannis, S., Simos, P. G., Rezaie, R., Fletcher, J. M., Cirino, P. T., & Papanicolaou, A. (2011). Dynamic task-specific brain network connectivity in children with severe reading difficulties. Neuroscience Letters, 488(2), 123-128. https://doi.org/10.1016/j.neulet.2010.11.013

Dynamic task-specific brain network connectivity in children with severe reading difficulties. / Vourkas, Michael; Micheloyannis, Sifis; Simos, Panagiotis G.; Rezaie, Roozbeh; Fletcher, Jack M.; Cirino, Paul T.; Papanicolaou, Andrew.

In: Neuroscience Letters, Vol. 488, No. 2, 20.01.2011, p. 123-128.

Research output: Contribution to journalArticle

Vourkas, M, Micheloyannis, S, Simos, PG, Rezaie, R, Fletcher, JM, Cirino, PT & Papanicolaou, A 2011, 'Dynamic task-specific brain network connectivity in children with severe reading difficulties', Neuroscience Letters, vol. 488, no. 2, pp. 123-128. https://doi.org/10.1016/j.neulet.2010.11.013
Vourkas, Michael ; Micheloyannis, Sifis ; Simos, Panagiotis G. ; Rezaie, Roozbeh ; Fletcher, Jack M. ; Cirino, Paul T. ; Papanicolaou, Andrew. / Dynamic task-specific brain network connectivity in children with severe reading difficulties. In: Neuroscience Letters. 2011 ; Vol. 488, No. 2. pp. 123-128.
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