Dynamics of Pneumocystis carinii‐Specific Immune Complexes in AIDS Patients with P. carinii Pneumonia

Research output: Contribution to journalArticle

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Abstract

Pneumocystis carinii‐specitic immune complexes were detected by immunoblot and enzyme‐linked immunosorbent assay (ELISA) in 53% of sera from Acquired Immunodeficiency Syndrome (AIDS) patients with P. carinii pneumonia (PCP). Resolution of glycoprotein antigenemia (50–55 kd = dominant species) appears to correlate with successful PCP drug therapy and recovery. An epitope map has been constructed from im‐munoblots of P. carinii hydrolysates and from human and murine scrum containing P. carinii antigens.

Original languageEnglish (US)
Pages (from-to)44S-46S
JournalThe Journal of Protozoology
Volume36
Issue number1
DOIs
StatePublished - Jan 1 1989

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Pneumocystis
Antigen-Antibody Complex
Pneumonia
Acquired Immunodeficiency Syndrome
Immunosorbents
Epitopes
Glycoproteins
Antigens
Drug Therapy
Serum

All Science Journal Classification (ASJC) codes

  • Parasitology

Cite this

Dynamics of Pneumocystis carinii‐Specific Immune Complexes in AIDS Patients with P. carinii Pneumonia. / Pifer, Linda.

In: The Journal of Protozoology, Vol. 36, No. 1, 01.01.1989, p. 44S-46S.

Research output: Contribution to journalArticle

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