Early effects of Helicobacter pylori infection in patients undergoing bariatric surgery

Archana Ramaswamy, Edward Lin, Bruce Ramshaw, C. Daniel Smith

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Hypothesis: Following weight loss surgery, many patients initially experience nonspecific foregut symptoms. Helicobacter pylori infection of the gastric remnant may be associated with foregut symptoms. Design: Inception cohort. Setting: University hospital. Patients: Ninety-nine consecutive patients being evaluated for weight loss surgery. Intervention: All patients underwent preoperative esophagogastroduodenoscopy and H pylori testing. Main Outcome Measures: Foregut symptoms were documented at routine post-weight loss surgery follow-up visits. Results: Preoperatively, 24% of patients tested positive for H pylori. Postoperative foregut symptoms were significant in 48% of the H pylori-positive group, and 19% of the H pylori-negative group (P=.02). This increase remained even after controlling for age, sex, preoperative presence of antritis, type of surgery performed, and body mass index (odds ratio, 3.6; 95% confidence interval,1.1-11.8). Patients with prolonged symptoms who tested positive for H pylori were given an eradication treatment. Conclusions: The prevalence of H pylon infection in patients undergoing weight loss surgery is high, and a significant proportion of them have postoperative foregut symptoms. Consideration should be given to H pylori treatment in these patients.

Original languageEnglish (US)
Pages (from-to)1094-1096
Number of pages3
JournalArchives of Surgery
Volume139
Issue number10
DOIs
StatePublished - Oct 1 2004

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Bariatric Surgery
Helicobacter Infections
Helicobacter pylori
Pylorus
Weight Loss
Gastric Stump
Digestive System Endoscopy
Body Mass Index
Odds Ratio
Outcome Assessment (Health Care)
Confidence Intervals
Therapeutics
Infection

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Early effects of Helicobacter pylori infection in patients undergoing bariatric surgery. / Ramaswamy, Archana; Lin, Edward; Ramshaw, Bruce; Smith, C. Daniel.

In: Archives of Surgery, Vol. 139, No. 10, 01.10.2004, p. 1094-1096.

Research output: Contribution to journalArticle

Ramaswamy, Archana ; Lin, Edward ; Ramshaw, Bruce ; Smith, C. Daniel. / Early effects of Helicobacter pylori infection in patients undergoing bariatric surgery. In: Archives of Surgery. 2004 ; Vol. 139, No. 10. pp. 1094-1096.
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