Ectopic brain tissue in the trigeminal nerve presenting as rapid-onset trigeminal neuralgia

Case report

Jeffrey H. Zimering, Jonathan J. Stone, Audrey Paulzak, John D. Markman, Mahlon Johnson, G. Edward Vates

Research output: Contribution to journalArticle

Abstract

The authors report the case of a 52-year-old man who presented with rapid-onset lancinating facial pain consistent with trigeminal neuralgia. Magnetic resonance imaging revealed a nonenhancing small lesion on the right trigeminal nerve concerning for an atypical schwannoma or neuroma. The patient underwent resection of the mass via a right retrosigmoid approach. His facial pain completely resolved immediately postoperatively and had not recurred at 6 months after surgery. The mass was consistent with normal brain tissue (neurons and glial cells) without evidence of mitoses. A final histopathological diagnosis of ectopic brain tissue with neural tissue demonstrating focal, chronic T-cell inflammation was made. The partial rhizotomy during resection was curative for the facial pain. To the authors' knowledge, this is the first report of neuroglial ectopia causing trigeminal neuralgia.

Original languageEnglish (US)
Pages (from-to)1063-1066
Number of pages4
JournalJournal of Neurosurgery
Volume129
Issue number4
DOIs
StatePublished - Oct 1 2018
Externally publishedYes

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Choristoma
Trigeminal Neuralgia
Facial Pain
Trigeminal Nerve
Brain
Rhizotomy
Neuroma
Neurilemmoma
Mitosis
Neuroglia
Magnetic Resonance Imaging
Inflammation
T-Lymphocytes
Neurons

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

Cite this

Ectopic brain tissue in the trigeminal nerve presenting as rapid-onset trigeminal neuralgia : Case report. / Zimering, Jeffrey H.; Stone, Jonathan J.; Paulzak, Audrey; Markman, John D.; Johnson, Mahlon; Vates, G. Edward.

In: Journal of Neurosurgery, Vol. 129, No. 4, 01.10.2018, p. 1063-1066.

Research output: Contribution to journalArticle

Zimering, Jeffrey H. ; Stone, Jonathan J. ; Paulzak, Audrey ; Markman, John D. ; Johnson, Mahlon ; Vates, G. Edward. / Ectopic brain tissue in the trigeminal nerve presenting as rapid-onset trigeminal neuralgia : Case report. In: Journal of Neurosurgery. 2018 ; Vol. 129, No. 4. pp. 1063-1066.
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