Editorial

PPIs and clopidogrel: The band plays on......

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

Controversy currently surrounds the issue of proton pump inhibitor (PPI)-clopidogrel co-therapy. Some studies have reported that PPIs increase the rate of adverse cardiovascular outcomes in clopidogrel users, although others have not confirmed this. The Food and Drug Administration has advised against the use of certain PPIs by patients who are on clopidogrel. In the first outcomes study from Europe to examine this issue, van Boxel and colleagues found an increased rate of adverse cardiovascularand gastrointestinaloutcomes among clopidogrel users taking a PPI. The most plausible explanation for this is that it reflects channeling bias.

Original languageEnglish (US)
Pages (from-to)2438-2439
Number of pages2
JournalAmerican Journal of Gastroenterology
Volume105
Issue number11
DOIs
StatePublished - Nov 1 2010
Externally publishedYes

Fingerprint

clopidogrel
Proton Pump Inhibitors
United States Food and Drug Administration
Outcome Assessment (Health Care)

All Science Journal Classification (ASJC) codes

  • Gastroenterology
  • Medicine(all)

Cite this

Editorial : PPIs and clopidogrel: The band plays on...... / Howden, Colin.

In: American Journal of Gastroenterology, Vol. 105, No. 11, 01.11.2010, p. 2438-2439.

Research output: Contribution to journalReview article

@article{1412f60dcb9940bfbadabb63d8a08f54,
title = "Editorial: PPIs and clopidogrel: The band plays on......",
abstract = "Controversy currently surrounds the issue of proton pump inhibitor (PPI)-clopidogrel co-therapy. Some studies have reported that PPIs increase the rate of adverse cardiovascular outcomes in clopidogrel users, although others have not confirmed this. The Food and Drug Administration has advised against the use of certain PPIs by patients who are on clopidogrel. In the first outcomes study from Europe to examine this issue, van Boxel and colleagues found an increased rate of adverse cardiovascularand gastrointestinaloutcomes among clopidogrel users taking a PPI. The most plausible explanation for this is that it reflects channeling bias.",
author = "Colin Howden",
year = "2010",
month = "11",
day = "1",
doi = "10.1038/ajg.2010.326",
language = "English (US)",
volume = "105",
pages = "2438--2439",
journal = "American Journal of Gastroenterology",
issn = "0002-9270",
publisher = "Nature Publishing Group",
number = "11",

}

TY - JOUR

T1 - Editorial

T2 - PPIs and clopidogrel: The band plays on......

AU - Howden, Colin

PY - 2010/11/1

Y1 - 2010/11/1

N2 - Controversy currently surrounds the issue of proton pump inhibitor (PPI)-clopidogrel co-therapy. Some studies have reported that PPIs increase the rate of adverse cardiovascular outcomes in clopidogrel users, although others have not confirmed this. The Food and Drug Administration has advised against the use of certain PPIs by patients who are on clopidogrel. In the first outcomes study from Europe to examine this issue, van Boxel and colleagues found an increased rate of adverse cardiovascularand gastrointestinaloutcomes among clopidogrel users taking a PPI. The most plausible explanation for this is that it reflects channeling bias.

AB - Controversy currently surrounds the issue of proton pump inhibitor (PPI)-clopidogrel co-therapy. Some studies have reported that PPIs increase the rate of adverse cardiovascular outcomes in clopidogrel users, although others have not confirmed this. The Food and Drug Administration has advised against the use of certain PPIs by patients who are on clopidogrel. In the first outcomes study from Europe to examine this issue, van Boxel and colleagues found an increased rate of adverse cardiovascularand gastrointestinaloutcomes among clopidogrel users taking a PPI. The most plausible explanation for this is that it reflects channeling bias.

UR - http://www.scopus.com/inward/record.url?scp=78149243268&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78149243268&partnerID=8YFLogxK

U2 - 10.1038/ajg.2010.326

DO - 10.1038/ajg.2010.326

M3 - Review article

VL - 105

SP - 2438

EP - 2439

JO - American Journal of Gastroenterology

JF - American Journal of Gastroenterology

SN - 0002-9270

IS - 11

ER -