Effects of alcohol exposure during different periods of development

changes in hippocampal mossy fibers.

J. R. West, Kristin Hamre

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Exposure to 10-12 g/kg/day of alcohol either during days 1-10 or 11-21 of gestation had no detectable effect on hippocampal mossy fiber development. Exposing artificially reared rat pups to 7.0-7.5 g/kg/day of alcohol during days 1-10 postpartum dramatically altered the organization of the Timm-stained mossy fiber terminal field when the animals were examined as adults, suggesting that alcohol exposure during a period equivalent to the human third trimester is more deleterious to brain development than exposure during periods equivalent to either the first or second trimesters.

Original languageEnglish (US)
Pages (from-to)280-284
Number of pages5
JournalBrain Research
Volume349
Issue number1-2
StatePublished - Jan 1 1985
Externally publishedYes

Fingerprint

Hippocampal Mossy Fibers
Alcohols
Third Pregnancy Trimester
Second Pregnancy Trimester
First Pregnancy Trimester
Postpartum Period
Pregnancy
Brain

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Effects of alcohol exposure during different periods of development : changes in hippocampal mossy fibers. / West, J. R.; Hamre, Kristin.

In: Brain Research, Vol. 349, No. 1-2, 01.01.1985, p. 280-284.

Research output: Contribution to journalArticle

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