Electrocardiographic criteria for diagnosis of acute myocardial infarction in childhood

Jeffrey Towbin, J. Timothy Bricker, Arthur Garson

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55 Citations (Scopus)

Abstract

Myocardial infarction (MI), a common occurrence in adults, is generally considered to be rare in children. Electrocardiographic criteria for diagnosis of MI in adults are well known and accepted, but no general criteria exist for children. We report 37 autopsy-proved cases of transmural MI and electrocardiographic evidence of MI in 30 of these cases. A variety of conditions previously reported to produce "pseudo-infarction" are included in these cases of MI, including myocarditis, hypertrophic cardiomyopathy, and the cardiomyopathy of Duchenne's muscular dystrophy. Compilation of the electrocardiographic data in all patients allowed for the development of criteria for this diagnosis of MI in childhood, and include wide Q waves (>35 ms) with or without Q-wave notching, ST-segment elevation (>2 mm), and prolonged QT interval corrected for heart rate (QTc > 440 ms) with accompanying Q-wave abnormalities. With use of these electrocardiographic criteria, an additional 3 patients were subsequently diagnosed prospectively with MI and confirmed on autopsy. Pathologic evaluation confirmed the location of infarction predicted by the electrocardiograms in all 3 cases.

Original languageEnglish (US)
Pages (from-to)1545-1548
Number of pages4
JournalThe American journal of cardiology
Volume69
Issue number19
DOIs
StatePublished - Jun 15 1992
Externally publishedYes

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Myocardial Infarction
Infarction
Autopsy
Duchenne Muscular Dystrophy
Hypertrophic Cardiomyopathy
Myocarditis
Cardiomyopathies
Electrocardiography
Heart Rate

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Electrocardiographic criteria for diagnosis of acute myocardial infarction in childhood. / Towbin, Jeffrey; Bricker, J. Timothy; Garson, Arthur.

In: The American journal of cardiology, Vol. 69, No. 19, 15.06.1992, p. 1545-1548.

Research output: Contribution to journalArticle

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