Electrochemical Pretreatment of Carbon Fibers for in Vivo Electrochemistry

Effects on Sensitivity and Response Time

Jian Xing Feng, Kenneth Renner, Richard Kasser, Ralph N. Adams, Michael Brazell

Research output: Contribution to journalArticle

110 Citations (Scopus)

Abstract

Oxidative electrochemical pretreatment of carbon fibers greatly improves their sensitivity for in vivo electrochemical detection of catechoiamine species. It is shown that the extent of the anodic potential excursion in the pretreatment is a major factor in both the sensitivity and the response time of the resulting fiber electrode. The high sensitivity for neurotransmitter species such as dopamine appears mainly due to adsorption on the oxidized carbon filber surface states. Practical protocols for fiber electrodes to be used in in vivo brain studies are evaluated.

Original languageEnglish (US)
Pages (from-to)1863-1867
Number of pages5
JournalAnalytical Chemistry
Volume59
Issue number14
DOIs
StatePublished - Jan 1 1987

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Electrochemistry
Electrodes
Fibers
Surface states
Neurotransmitter Agents
Dopamine
Brain
Carbon
Adsorption
carbon fiber

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry

Cite this

Electrochemical Pretreatment of Carbon Fibers for in Vivo Electrochemistry : Effects on Sensitivity and Response Time. / Feng, Jian Xing; Renner, Kenneth; Kasser, Richard; Adams, Ralph N.; Brazell, Michael.

In: Analytical Chemistry, Vol. 59, No. 14, 01.01.1987, p. 1863-1867.

Research output: Contribution to journalArticle

Feng, Jian Xing ; Renner, Kenneth ; Kasser, Richard ; Adams, Ralph N. ; Brazell, Michael. / Electrochemical Pretreatment of Carbon Fibers for in Vivo Electrochemistry : Effects on Sensitivity and Response Time. In: Analytical Chemistry. 1987 ; Vol. 59, No. 14. pp. 1863-1867.
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