Electrocoating carbon fiber microelectrodes with Nafion improves selectivity for electroactive neurotransmitters

M. P. Brazell, Richard Kasser, K. J. Renner, J. Feng, B. Moghaddam, R. N. Adams

Research output: Contribution to journalArticle

121 Citations (Scopus)

Abstract

A method which improves carbon fiber microelectrode selectivity for cationic amines by electrocoating the fiber with a thin film of the ionic polymer, Nafion, is described. The selectivity and response speed of these electrodes for the detection of electroactive cationic and anionic species found in brain extracellular fluid was evaluated using differential pulse voltammetry and chronoamperometry and compared to uncoated fibers. Carbon fiber microelectrodes electrocoated with Nafion are highly sensitive to cationic amines such as dopamine and serotonin and have minimal sensitivity to anions such as ascorbic acid and uric acid at physiological concentrations.

Original languageEnglish (US)
Pages (from-to)167-172
Number of pages6
JournalJournal of Neuroscience Methods
Volume22
Issue number2
DOIs
StatePublished - Jan 1 1987

Fingerprint

Microelectrodes
Amines
Neurotransmitter Agents
Extracellular Fluid
Uric Acid
Ascorbic Acid
Anions
Dopamine
Serotonin
Polymers
Electrodes
Brain
carbon fiber
perfluorosulfonic acid

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Electrocoating carbon fiber microelectrodes with Nafion improves selectivity for electroactive neurotransmitters. / Brazell, M. P.; Kasser, Richard; Renner, K. J.; Feng, J.; Moghaddam, B.; Adams, R. N.

In: Journal of Neuroscience Methods, Vol. 22, No. 2, 01.01.1987, p. 167-172.

Research output: Contribution to journalArticle

Brazell, M. P. ; Kasser, Richard ; Renner, K. J. ; Feng, J. ; Moghaddam, B. ; Adams, R. N. / Electrocoating carbon fiber microelectrodes with Nafion improves selectivity for electroactive neurotransmitters. In: Journal of Neuroscience Methods. 1987 ; Vol. 22, No. 2. pp. 167-172.
@article{4b718aeca8044c659908720b98167f46,
title = "Electrocoating carbon fiber microelectrodes with Nafion improves selectivity for electroactive neurotransmitters",
abstract = "A method which improves carbon fiber microelectrode selectivity for cationic amines by electrocoating the fiber with a thin film of the ionic polymer, Nafion, is described. The selectivity and response speed of these electrodes for the detection of electroactive cationic and anionic species found in brain extracellular fluid was evaluated using differential pulse voltammetry and chronoamperometry and compared to uncoated fibers. Carbon fiber microelectrodes electrocoated with Nafion are highly sensitive to cationic amines such as dopamine and serotonin and have minimal sensitivity to anions such as ascorbic acid and uric acid at physiological concentrations.",
author = "Brazell, {M. P.} and Richard Kasser and Renner, {K. J.} and J. Feng and B. Moghaddam and Adams, {R. N.}",
year = "1987",
month = "1",
day = "1",
doi = "10.1016/0165-0270(87)90011-2",
language = "English (US)",
volume = "22",
pages = "167--172",
journal = "Journal of Neuroscience Methods",
issn = "0165-0270",
publisher = "Elsevier",
number = "2",

}

TY - JOUR

T1 - Electrocoating carbon fiber microelectrodes with Nafion improves selectivity for electroactive neurotransmitters

AU - Brazell, M. P.

AU - Kasser, Richard

AU - Renner, K. J.

AU - Feng, J.

AU - Moghaddam, B.

AU - Adams, R. N.

PY - 1987/1/1

Y1 - 1987/1/1

N2 - A method which improves carbon fiber microelectrode selectivity for cationic amines by electrocoating the fiber with a thin film of the ionic polymer, Nafion, is described. The selectivity and response speed of these electrodes for the detection of electroactive cationic and anionic species found in brain extracellular fluid was evaluated using differential pulse voltammetry and chronoamperometry and compared to uncoated fibers. Carbon fiber microelectrodes electrocoated with Nafion are highly sensitive to cationic amines such as dopamine and serotonin and have minimal sensitivity to anions such as ascorbic acid and uric acid at physiological concentrations.

AB - A method which improves carbon fiber microelectrode selectivity for cationic amines by electrocoating the fiber with a thin film of the ionic polymer, Nafion, is described. The selectivity and response speed of these electrodes for the detection of electroactive cationic and anionic species found in brain extracellular fluid was evaluated using differential pulse voltammetry and chronoamperometry and compared to uncoated fibers. Carbon fiber microelectrodes electrocoated with Nafion are highly sensitive to cationic amines such as dopamine and serotonin and have minimal sensitivity to anions such as ascorbic acid and uric acid at physiological concentrations.

UR - http://www.scopus.com/inward/record.url?scp=0023617803&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023617803&partnerID=8YFLogxK

U2 - 10.1016/0165-0270(87)90011-2

DO - 10.1016/0165-0270(87)90011-2

M3 - Article

VL - 22

SP - 167

EP - 172

JO - Journal of Neuroscience Methods

JF - Journal of Neuroscience Methods

SN - 0165-0270

IS - 2

ER -