Electroencephalogram discharges in atypical cognitive development

Richard E. Frye, Ian Butler, David Strickland, Edwardo Castillo, Andrew Papanicolaou

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

To investigate the significance of electroencephalogram (EEG) discharges and their treatment, we retrospectively reviewed the charts of 22 children with atypical cognitive development that did not respond to standard educational therapy and demonstrated discharges on EEG. Most children demonstrated no obvious symptoms of seizures, and developmental regression and/or fluctuations were uncommon. The majority of children demonstrated a language and attention disorder and autism symptomatology and had multifocal discharges on EEGs. Of the 20 patients treated with antiepileptic medications, 70% demonstrated definite improvement within 1 clinic visit. This study suggests that children with EEG discharges and developmental cognitive disorders demonstrate a unique pattern of symptomatology and discharges on EEG. This study suggests that children with developmental cognitive disorders that do not respond to standard therapy may benefit from screening with an EEG and a trial of antiepileptic mediation if discharges are detected.

Original languageEnglish (US)
Pages (from-to)556-566
Number of pages11
JournalJournal of Child Neurology
Volume25
Issue number5
DOIs
StatePublished - May 1 2010

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Electroencephalography
Anticonvulsants
Language Disorders
Ambulatory Care
Autistic Disorder
Seizures
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Frye, R. E., Butler, I., Strickland, D., Castillo, E., & Papanicolaou, A. (2010). Electroencephalogram discharges in atypical cognitive development. Journal of Child Neurology, 25(5), 556-566. https://doi.org/10.1177/0883073809344743

Electroencephalogram discharges in atypical cognitive development. / Frye, Richard E.; Butler, Ian; Strickland, David; Castillo, Edwardo; Papanicolaou, Andrew.

In: Journal of Child Neurology, Vol. 25, No. 5, 01.05.2010, p. 556-566.

Research output: Contribution to journalArticle

Frye, RE, Butler, I, Strickland, D, Castillo, E & Papanicolaou, A 2010, 'Electroencephalogram discharges in atypical cognitive development', Journal of Child Neurology, vol. 25, no. 5, pp. 556-566. https://doi.org/10.1177/0883073809344743
Frye RE, Butler I, Strickland D, Castillo E, Papanicolaou A. Electroencephalogram discharges in atypical cognitive development. Journal of Child Neurology. 2010 May 1;25(5):556-566. https://doi.org/10.1177/0883073809344743
Frye, Richard E. ; Butler, Ian ; Strickland, David ; Castillo, Edwardo ; Papanicolaou, Andrew. / Electroencephalogram discharges in atypical cognitive development. In: Journal of Child Neurology. 2010 ; Vol. 25, No. 5. pp. 556-566.
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