Electrophysiology of rat thalamo-cortical relay neurons

an in vivo intracellular recordingf and labeling study

Hitoshi Kita, S. T. Kitai

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Membrane properties and responses to frontal cortical stimulation were studied on electrophysiologically and morphologically identified thalamo-cortical neurons in anesthetized rats. Those neurons generated membrane responses resembling the low-threshold Ca-spike, gK(Ca) and IA that have been previously demonstrated in in vitro studies of thalamic neurons. Stimulation of the frontal cortex evoked a sequence of responses; antidromic spike, initial depolarization, long duration hyperpolarization and a short period of depolarization. The initial depolarization was considered to be a monosynaptic excitatory postsynaptic potential (EPSP) which overlapped with an inhibitory postsynaptic potential (IPSP). Major constituents of the long duration hyperpolarization were considered to be short duration IPSPs and long duration disfacilitations of cortical inputs.

Original languageEnglish (US)
Pages (from-to)80-89
Number of pages10
JournalBrain Research
Volume371
Issue number1
DOIs
StatePublished - Apr 16 1986

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Electrophysiology
Inhibitory Postsynaptic Potentials
Neurons
Membranes
Excitatory Postsynaptic Potentials
Frontal Lobe

All Science Journal Classification (ASJC) codes

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Electrophysiology of rat thalamo-cortical relay neurons : an in vivo intracellular recordingf and labeling study. / Kita, Hitoshi; Kitai, S. T.

In: Brain Research, Vol. 371, No. 1, 16.04.1986, p. 80-89.

Research output: Contribution to journalArticle

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