Endovascular management of arteriovenous malformations and other intracranial arteriovenous shunts in neonates, infants, and children

Alejandro Berenstein, Rafael Ortiz, Yasunari Niimi, Lucas Elijovich, Johanna Fifi, Mary Madrid, Saadi Ghatan, Walter Molofsky

Research output: Contribution to journalReview article

43 Citations (Scopus)

Abstract

Purpose: We discuss the management of cerebral arteriovenous shunts in neonates, infants, and children, with emphasis on our experience with pediatric cerebral arteriovenous malformations (AVMs). The management of vein of Galen malformations is discussed in a separate chapter. Methods: An all-inclusive retrospective chart review of the endovascular surgery operative record database at the Hyman Newman Institute for Neurology and Neurosurgery at Roosevelt Hospital in NYC was conducted. All consecutive pediatric patients (newborn to 18 years of age) with intracranial arteriovenous shunts who presented from January 1, 2004 to June 16, 2009 were included. Results: A total of 151 consecutive pediatric patients with intracranial arteriovenous shunts were evaluated from the period of January 1, 2004 to June 16, 2009. This included 56 patients with vein of Galen malformations, 48 cerebral AVMs, 11 patients with pial arteriovenous fistulae, six patients with dural arteriovenous malformations, and 30 patients with mixed intracranial vascular malformations. Forty-four patients underwent a total of 163 endovascular embolizations. The complications rate for endovascular embolizations was 6.7% (11 in 163), 5.5% with temporary complications and 1.2% with permanent complications. The mortality rate for the group of patients (excluding patients with vein of Galen malformations) that underwent endovascular embolizations was 0.0%. Conclusions: Careful clinical observation and timely intervention are important in the management of pediatric patients with intracranial arteriovenous shunts. Trans-arterial endovascular embolization with liquid embolic agents is the treatment of choice for safe stabilization and/or improvement of symptoms in the group of pediatric patients with intracranial arteriovenous malformations.

Original languageEnglish (US)
Pages (from-to)1345-1358
Number of pages14
JournalChild's Nervous System
Volume26
Issue number10
DOIs
StatePublished - Oct 1 2010

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Intracranial Arteriovenous Malformations
Newborn Infant
Vein of Galen Malformations
Pediatrics
Vascular Malformations
Arteriovenous Malformations
Arteriovenous Fistula
Neurosurgery
Neurology

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Endovascular management of arteriovenous malformations and other intracranial arteriovenous shunts in neonates, infants, and children. / Berenstein, Alejandro; Ortiz, Rafael; Niimi, Yasunari; Elijovich, Lucas; Fifi, Johanna; Madrid, Mary; Ghatan, Saadi; Molofsky, Walter.

In: Child's Nervous System, Vol. 26, No. 10, 01.10.2010, p. 1345-1358.

Research output: Contribution to journalReview article

Berenstein, Alejandro ; Ortiz, Rafael ; Niimi, Yasunari ; Elijovich, Lucas ; Fifi, Johanna ; Madrid, Mary ; Ghatan, Saadi ; Molofsky, Walter. / Endovascular management of arteriovenous malformations and other intracranial arteriovenous shunts in neonates, infants, and children. In: Child's Nervous System. 2010 ; Vol. 26, No. 10. pp. 1345-1358.
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T1 - Endovascular management of arteriovenous malformations and other intracranial arteriovenous shunts in neonates, infants, and children

AU - Berenstein, Alejandro

AU - Ortiz, Rafael

AU - Niimi, Yasunari

AU - Elijovich, Lucas

AU - Fifi, Johanna

AU - Madrid, Mary

AU - Ghatan, Saadi

AU - Molofsky, Walter

PY - 2010/10/1

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N2 - Purpose: We discuss the management of cerebral arteriovenous shunts in neonates, infants, and children, with emphasis on our experience with pediatric cerebral arteriovenous malformations (AVMs). The management of vein of Galen malformations is discussed in a separate chapter. Methods: An all-inclusive retrospective chart review of the endovascular surgery operative record database at the Hyman Newman Institute for Neurology and Neurosurgery at Roosevelt Hospital in NYC was conducted. All consecutive pediatric patients (newborn to 18 years of age) with intracranial arteriovenous shunts who presented from January 1, 2004 to June 16, 2009 were included. Results: A total of 151 consecutive pediatric patients with intracranial arteriovenous shunts were evaluated from the period of January 1, 2004 to June 16, 2009. This included 56 patients with vein of Galen malformations, 48 cerebral AVMs, 11 patients with pial arteriovenous fistulae, six patients with dural arteriovenous malformations, and 30 patients with mixed intracranial vascular malformations. Forty-four patients underwent a total of 163 endovascular embolizations. The complications rate for endovascular embolizations was 6.7% (11 in 163), 5.5% with temporary complications and 1.2% with permanent complications. The mortality rate for the group of patients (excluding patients with vein of Galen malformations) that underwent endovascular embolizations was 0.0%. Conclusions: Careful clinical observation and timely intervention are important in the management of pediatric patients with intracranial arteriovenous shunts. Trans-arterial endovascular embolization with liquid embolic agents is the treatment of choice for safe stabilization and/or improvement of symptoms in the group of pediatric patients with intracranial arteriovenous malformations.

AB - Purpose: We discuss the management of cerebral arteriovenous shunts in neonates, infants, and children, with emphasis on our experience with pediatric cerebral arteriovenous malformations (AVMs). The management of vein of Galen malformations is discussed in a separate chapter. Methods: An all-inclusive retrospective chart review of the endovascular surgery operative record database at the Hyman Newman Institute for Neurology and Neurosurgery at Roosevelt Hospital in NYC was conducted. All consecutive pediatric patients (newborn to 18 years of age) with intracranial arteriovenous shunts who presented from January 1, 2004 to June 16, 2009 were included. Results: A total of 151 consecutive pediatric patients with intracranial arteriovenous shunts were evaluated from the period of January 1, 2004 to June 16, 2009. This included 56 patients with vein of Galen malformations, 48 cerebral AVMs, 11 patients with pial arteriovenous fistulae, six patients with dural arteriovenous malformations, and 30 patients with mixed intracranial vascular malformations. Forty-four patients underwent a total of 163 endovascular embolizations. The complications rate for endovascular embolizations was 6.7% (11 in 163), 5.5% with temporary complications and 1.2% with permanent complications. The mortality rate for the group of patients (excluding patients with vein of Galen malformations) that underwent endovascular embolizations was 0.0%. Conclusions: Careful clinical observation and timely intervention are important in the management of pediatric patients with intracranial arteriovenous shunts. Trans-arterial endovascular embolization with liquid embolic agents is the treatment of choice for safe stabilization and/or improvement of symptoms in the group of pediatric patients with intracranial arteriovenous malformations.

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M3 - Review article

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JO - Child's Nervous System

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SN - 0256-7040

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