Enhancement of binding of quaternary ammonium derivatives of chlorpromaxine to dopamine D-2 receptors by the addition of a H-bonding group

Kimberly M. Markovich, Tahira Farooqui, Lane J. Wallace, Norman J. Uretsky, Duane Miller

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Several permanently charged analogs of chloropromazine were synthesized and evaluated for their binding to dopamine D-2 receptors.

Original languageEnglish (US)
Pages (from-to)1241-1244
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume3
Issue number6
DOIs
StatePublished - Jan 1 1993

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Ammonium Compounds
Dopamine
Derivatives

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science

Cite this

Enhancement of binding of quaternary ammonium derivatives of chlorpromaxine to dopamine D-2 receptors by the addition of a H-bonding group. / Markovich, Kimberly M.; Farooqui, Tahira; Wallace, Lane J.; Uretsky, Norman J.; Miller, Duane.

In: Bioorganic and Medicinal Chemistry Letters, Vol. 3, No. 6, 01.01.1993, p. 1241-1244.

Research output: Contribution to journalArticle

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