Eosinophilic Esophagitis: Diagnosis and Management

Jay Lieberman, Mirna Chehade

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

Eosinophilic esophagitis is a clinicopathologic disease that can present with a constellation of upper gastrointestinal symptoms and endoscopic findings in conjunction with significant infiltration of the esophageal tissue with eosinophils. Clinical and histologic resolution of the disease can be seen with dietary restriction therapies and systemic and topical corticosteroids. Because most patients have an atopic background and the disease seems to have an underlying T-helper type 2 pathogenesis, allergists and gastroenterologists need to be familiar with the diagnosis and management of this disease. In this review, clinical characteristics, endoscopic and histologic findings, and available therapy options are discussed.

Original languageEnglish (US)
Pages (from-to)67-81
Number of pages15
JournalImmunology and Allergy Clinics of North America
Volume32
Issue number1
DOIs
StatePublished - Feb 1 2012
Externally publishedYes

Fingerprint

Eosinophilic Esophagitis
Disease Management
Eosinophils
Adrenal Cortex Hormones
Therapeutics

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

Cite this

Eosinophilic Esophagitis : Diagnosis and Management. / Lieberman, Jay; Chehade, Mirna.

In: Immunology and Allergy Clinics of North America, Vol. 32, No. 1, 01.02.2012, p. 67-81.

Research output: Contribution to journalReview article

@article{115f48ded8444cda9b05ceb80086d946,
title = "Eosinophilic Esophagitis: Diagnosis and Management",
abstract = "Eosinophilic esophagitis is a clinicopathologic disease that can present with a constellation of upper gastrointestinal symptoms and endoscopic findings in conjunction with significant infiltration of the esophageal tissue with eosinophils. Clinical and histologic resolution of the disease can be seen with dietary restriction therapies and systemic and topical corticosteroids. Because most patients have an atopic background and the disease seems to have an underlying T-helper type 2 pathogenesis, allergists and gastroenterologists need to be familiar with the diagnosis and management of this disease. In this review, clinical characteristics, endoscopic and histologic findings, and available therapy options are discussed.",
author = "Jay Lieberman and Mirna Chehade",
year = "2012",
month = "2",
day = "1",
doi = "10.1016/j.iac.2011.11.006",
language = "English (US)",
volume = "32",
pages = "67--81",
journal = "Immunology and Allergy Clinics of North America",
issn = "0889-8561",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Eosinophilic Esophagitis

T2 - Diagnosis and Management

AU - Lieberman, Jay

AU - Chehade, Mirna

PY - 2012/2/1

Y1 - 2012/2/1

N2 - Eosinophilic esophagitis is a clinicopathologic disease that can present with a constellation of upper gastrointestinal symptoms and endoscopic findings in conjunction with significant infiltration of the esophageal tissue with eosinophils. Clinical and histologic resolution of the disease can be seen with dietary restriction therapies and systemic and topical corticosteroids. Because most patients have an atopic background and the disease seems to have an underlying T-helper type 2 pathogenesis, allergists and gastroenterologists need to be familiar with the diagnosis and management of this disease. In this review, clinical characteristics, endoscopic and histologic findings, and available therapy options are discussed.

AB - Eosinophilic esophagitis is a clinicopathologic disease that can present with a constellation of upper gastrointestinal symptoms and endoscopic findings in conjunction with significant infiltration of the esophageal tissue with eosinophils. Clinical and histologic resolution of the disease can be seen with dietary restriction therapies and systemic and topical corticosteroids. Because most patients have an atopic background and the disease seems to have an underlying T-helper type 2 pathogenesis, allergists and gastroenterologists need to be familiar with the diagnosis and management of this disease. In this review, clinical characteristics, endoscopic and histologic findings, and available therapy options are discussed.

UR - http://www.scopus.com/inward/record.url?scp=84855824516&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84855824516&partnerID=8YFLogxK

U2 - 10.1016/j.iac.2011.11.006

DO - 10.1016/j.iac.2011.11.006

M3 - Review article

C2 - 22244233

AN - SCOPUS:84855824516

VL - 32

SP - 67

EP - 81

JO - Immunology and Allergy Clinics of North America

JF - Immunology and Allergy Clinics of North America

SN - 0889-8561

IS - 1

ER -