Ethotoin in seizures of childhood and adolescence

Charles A. Carter, Richard Helms, Robert Boehm

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Ethotoin is an anticonvulsant that was considered minimally effective when introduced, but due to its apparent lack of side effects, there has been renewed interest in the drug for use in generalized and psychomotor seizures. We have characterized the pharmacokinetics of ethotoin in children and have found nonlinearity. Seizures were controlled in 16 of 17 patients, and there were no side effects reported. Gingival hyperplasia due to previous phenytoin therapy improved in all cases.

Original languageEnglish (US)
Pages (from-to)791-795
Number of pages5
JournalNeurology
Volume34
Issue number6
StatePublished - Jan 1 1984

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Seizures
Gingival Hyperplasia
Phenytoin
Anticonvulsants
Pharmacokinetics
Pharmaceutical Preparations
ethotoin
Therapeutics

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Carter, C. A., Helms, R., & Boehm, R. (1984). Ethotoin in seizures of childhood and adolescence. Neurology, 34(6), 791-795.

Ethotoin in seizures of childhood and adolescence. / Carter, Charles A.; Helms, Richard; Boehm, Robert.

In: Neurology, Vol. 34, No. 6, 01.01.1984, p. 791-795.

Research output: Contribution to journalArticle

Carter, CA, Helms, R & Boehm, R 1984, 'Ethotoin in seizures of childhood and adolescence', Neurology, vol. 34, no. 6, pp. 791-795.
Carter CA, Helms R, Boehm R. Ethotoin in seizures of childhood and adolescence. Neurology. 1984 Jan 1;34(6):791-795.
Carter, Charles A. ; Helms, Richard ; Boehm, Robert. / Ethotoin in seizures of childhood and adolescence. In: Neurology. 1984 ; Vol. 34, No. 6. pp. 791-795.
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