Evaluation of acute cerebral ischemia for anticoagulant therapy

Computed tomography or lumbar puncture

Robert L. Ruff, John Dougherty

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Of 217 patients with clinical diagnosis of acute stroke 23% had nonischemic lesions diagnosed by computed tomography (CT) or lumbar puncture (LP). CT demonstrated all 37 cases of intracerebral hemorrhagic lesions; 9 were detected by LP. CT failed to demonstrate 8 of 17 cases of subarachnoid hemorrhage, but only 1 of these lacked headache or stiff neck. In 7 of 342 patients who were treated with anticoagulants after LP, spinal hematoma followed LP (5 with paraparesis). CT evaluation reduced the incidence of fatal cerebral hemorrhage during anticoagulant therapy of acute stroke. However, even if patients were evaluated with both CT and LP, the incidence of fatal cerebral hemorrhage resulting from intravenous anticoagulant therapy was 2.4%.

Original languageEnglish (US)
Pages (from-to)736-740
Number of pages5
JournalNeurology
Volume31
Issue number6
StatePublished - Jan 1 1981
Externally publishedYes

Fingerprint

Spinal Puncture
Brain Ischemia
Anticoagulants
Tomography
Cerebral Hemorrhage
Stroke
Paraparesis
Therapeutics
Incidence
Subarachnoid Hemorrhage
Hematoma
Headache
Neck

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Evaluation of acute cerebral ischemia for anticoagulant therapy : Computed tomography or lumbar puncture. / Ruff, Robert L.; Dougherty, John.

In: Neurology, Vol. 31, No. 6, 01.01.1981, p. 736-740.

Research output: Contribution to journalArticle

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