Evaluation of biodegradable adjunctive therapy for extremity wound infection reduction

J. Jennings, S. Noel, B. Reves, K. Smith, S. Jackson, J. Bumgardner, W. Haggard, H. Courtney, J. Wenke

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Advances in surgical techniques, fixation devices, and hemorrhage control have improved functional outcomes in the field of extremity injury treatment. However, infection has become a primary concern, as it can lead to device failure, amputation, or death. Risk of infection may be lowered by local delivery of antibiotics, for which several carrier vehicles are available. Used as an adjunct to currently-used principles of debridement and lavage, local delivery systems have demonstrated efficacy, safety, and convenience for treatment of complex wounds. In this work, differences and modifications of various types of local antibiotic delivery systems are explored. Performance evaluations described are useful in the development of new carriers and in the selection of clinical therapies.

Original languageEnglish (US)
Title of host publicationMedical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference
Pages117-122
Number of pages6
StatePublished - Aug 26 2010
Event5th Materials and Processes for Medical Devices Conference, MPMD - Minneapolis, MN, United States
Duration: Aug 10 2009Aug 12 2009

Other

Other5th Materials and Processes for Medical Devices Conference, MPMD
CountryUnited States
CityMinneapolis, MN
Period8/10/098/12/09

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Antibiotics
Anti-Bacterial Agents

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Materials Chemistry

Cite this

Jennings, J., Noel, S., Reves, B., Smith, K., Jackson, S., Bumgardner, J., ... Wenke, J. (2010). Evaluation of biodegradable adjunctive therapy for extremity wound infection reduction. In Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference (pp. 117-122)

Evaluation of biodegradable adjunctive therapy for extremity wound infection reduction. / Jennings, J.; Noel, S.; Reves, B.; Smith, K.; Jackson, S.; Bumgardner, J.; Haggard, W.; Courtney, H.; Wenke, J.

Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference. 2010. p. 117-122.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Jennings, J, Noel, S, Reves, B, Smith, K, Jackson, S, Bumgardner, J, Haggard, W, Courtney, H & Wenke, J 2010, Evaluation of biodegradable adjunctive therapy for extremity wound infection reduction. in Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference. pp. 117-122, 5th Materials and Processes for Medical Devices Conference, MPMD, Minneapolis, MN, United States, 8/10/09.
Jennings J, Noel S, Reves B, Smith K, Jackson S, Bumgardner J et al. Evaluation of biodegradable adjunctive therapy for extremity wound infection reduction. In Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference. 2010. p. 117-122
Jennings, J. ; Noel, S. ; Reves, B. ; Smith, K. ; Jackson, S. ; Bumgardner, J. ; Haggard, W. ; Courtney, H. ; Wenke, J. / Evaluation of biodegradable adjunctive therapy for extremity wound infection reduction. Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference. 2010. pp. 117-122
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