Evaluation of detection methods and values of circulating vascular endothelial growth factor in lung cancer

Sumin Guo, Michael Martin, Cheng Tian, Jinglin Cui, Lishi Wang, Shucai Wu, Weikuan Gu

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Lung cancer is the deadliest cancer in the world. Angiogenesis plays a crucial role of the incidence, progression, and metastasis in lung cancer. Angiogenesis inhibitors are used to treat non-small cell lung cancer (NSCLC) patients, and the molecular biomarkers are also being assessed to predict treatment response/therapeutic response and patients' prognosis. Vascular endothelial growth factor (VEGF) is a signal protein produced by cells that stimulates angiogenesis. Due to its predictive values of prognosis on NSCLC, a large number of methods have been developed and evaluated to detect VEGF levels in a variety of studies. In this article, we review the detection methods designed to measure the VEGF levels in different body fluids and prognosticate the value of VEGF in treatment, diagnosis and survival in lung cancer.

Original languageEnglish (US)
Pages (from-to)1287-1300
Number of pages14
JournalJournal of Cancer
Volume9
Issue number7
DOIs
StatePublished - Jan 1 2018

Fingerprint

Vascular Endothelial Growth Factor A
Lung Neoplasms
Non-Small Cell Lung Carcinoma
Angiogenesis Inhibitors
Body Fluids
Therapeutics
Biomarkers
Neoplasm Metastasis
Survival
Incidence
Neoplasms
Proteins

All Science Journal Classification (ASJC) codes

  • Oncology

Cite this

Evaluation of detection methods and values of circulating vascular endothelial growth factor in lung cancer. / Guo, Sumin; Martin, Michael; Tian, Cheng; Cui, Jinglin; Wang, Lishi; Wu, Shucai; Gu, Weikuan.

In: Journal of Cancer, Vol. 9, No. 7, 01.01.2018, p. 1287-1300.

Research output: Contribution to journalReview article

Guo, Sumin ; Martin, Michael ; Tian, Cheng ; Cui, Jinglin ; Wang, Lishi ; Wu, Shucai ; Gu, Weikuan. / Evaluation of detection methods and values of circulating vascular endothelial growth factor in lung cancer. In: Journal of Cancer. 2018 ; Vol. 9, No. 7. pp. 1287-1300.
@article{ecb669aefe184e7caac5c62f70671594,
title = "Evaluation of detection methods and values of circulating vascular endothelial growth factor in lung cancer",
abstract = "Lung cancer is the deadliest cancer in the world. Angiogenesis plays a crucial role of the incidence, progression, and metastasis in lung cancer. Angiogenesis inhibitors are used to treat non-small cell lung cancer (NSCLC) patients, and the molecular biomarkers are also being assessed to predict treatment response/therapeutic response and patients' prognosis. Vascular endothelial growth factor (VEGF) is a signal protein produced by cells that stimulates angiogenesis. Due to its predictive values of prognosis on NSCLC, a large number of methods have been developed and evaluated to detect VEGF levels in a variety of studies. In this article, we review the detection methods designed to measure the VEGF levels in different body fluids and prognosticate the value of VEGF in treatment, diagnosis and survival in lung cancer.",
author = "Sumin Guo and Michael Martin and Cheng Tian and Jinglin Cui and Lishi Wang and Shucai Wu and Weikuan Gu",
year = "2018",
month = "1",
day = "1",
doi = "10.7150/jca.22020",
language = "English (US)",
volume = "9",
pages = "1287--1300",
journal = "Journal of Cancer",
issn = "1837-9664",
publisher = "Ivyspring International Publisher",
number = "7",

}

TY - JOUR

T1 - Evaluation of detection methods and values of circulating vascular endothelial growth factor in lung cancer

AU - Guo, Sumin

AU - Martin, Michael

AU - Tian, Cheng

AU - Cui, Jinglin

AU - Wang, Lishi

AU - Wu, Shucai

AU - Gu, Weikuan

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Lung cancer is the deadliest cancer in the world. Angiogenesis plays a crucial role of the incidence, progression, and metastasis in lung cancer. Angiogenesis inhibitors are used to treat non-small cell lung cancer (NSCLC) patients, and the molecular biomarkers are also being assessed to predict treatment response/therapeutic response and patients' prognosis. Vascular endothelial growth factor (VEGF) is a signal protein produced by cells that stimulates angiogenesis. Due to its predictive values of prognosis on NSCLC, a large number of methods have been developed and evaluated to detect VEGF levels in a variety of studies. In this article, we review the detection methods designed to measure the VEGF levels in different body fluids and prognosticate the value of VEGF in treatment, diagnosis and survival in lung cancer.

AB - Lung cancer is the deadliest cancer in the world. Angiogenesis plays a crucial role of the incidence, progression, and metastasis in lung cancer. Angiogenesis inhibitors are used to treat non-small cell lung cancer (NSCLC) patients, and the molecular biomarkers are also being assessed to predict treatment response/therapeutic response and patients' prognosis. Vascular endothelial growth factor (VEGF) is a signal protein produced by cells that stimulates angiogenesis. Due to its predictive values of prognosis on NSCLC, a large number of methods have been developed and evaluated to detect VEGF levels in a variety of studies. In this article, we review the detection methods designed to measure the VEGF levels in different body fluids and prognosticate the value of VEGF in treatment, diagnosis and survival in lung cancer.

UR - http://www.scopus.com/inward/record.url?scp=85044590445&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85044590445&partnerID=8YFLogxK

U2 - 10.7150/jca.22020

DO - 10.7150/jca.22020

M3 - Review article

VL - 9

SP - 1287

EP - 1300

JO - Journal of Cancer

JF - Journal of Cancer

SN - 1837-9664

IS - 7

ER -