Evaluation of intravenous acetaminophen on length of stay in abdominal surgery patients

Tyler C. Madere, Jennifer B. Mendez, Sarah T. Nordmeyer, Robert Heidel, Leslie Hamilton

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: The objective of this study is to evaluate the effect of intravenous acetaminophen on length of stay (LOS) in abdominal surgery patients. Methods: This retrospective, cohort chart review evaluated patients who underwent colon resection or pancreaticoduodenectomy between January 1, 2010 and August 31, 2013. The primary outcome is postoperative LOS. Secondary outcomes include opioid use, pain scores, and naloxone or laxative use. Patients who received intravenous acetaminophen were compared to patients who did not. Results: A total of 329 patients were included, with 269 in the non-acetaminophen group compared to 60 patients in the acetaminophen group. There was no difference in postoperative LOS (9.2 s vs 9.1 days; P = .90). Postoperative LOS was also similar when controlling for surgery type. The acetaminophen group had reduced opioid consumption in the first 24 hours postoperatively (P = .02). However, pain scores were higher in the acetaminophen group, both in the first 24 hours (P = .007) and throughout the hospital stay (P < .001). Other clinical outcomes were similar between groups. Conclusion: Intravenous acetaminophen was not associated with a decreased postoperative LOS at our institution.

Original languageEnglish (US)
Pages (from-to)230-236
Number of pages7
JournalHospital Pharmacy
Volume51
Issue number3
DOIs
StatePublished - Mar 1 2016

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Acetaminophen
Surgery
Length of Stay
Opioid Analgesics
Pain
Laxatives
Pancreaticoduodenectomy
Naloxone
Colon

All Science Journal Classification (ASJC) codes

  • Pharmacy
  • Pharmacology
  • Pharmacology (medical)

Cite this

Evaluation of intravenous acetaminophen on length of stay in abdominal surgery patients. / Madere, Tyler C.; Mendez, Jennifer B.; Nordmeyer, Sarah T.; Heidel, Robert; Hamilton, Leslie.

In: Hospital Pharmacy, Vol. 51, No. 3, 01.03.2016, p. 230-236.

Research output: Contribution to journalArticle

Madere, Tyler C. ; Mendez, Jennifer B. ; Nordmeyer, Sarah T. ; Heidel, Robert ; Hamilton, Leslie. / Evaluation of intravenous acetaminophen on length of stay in abdominal surgery patients. In: Hospital Pharmacy. 2016 ; Vol. 51, No. 3. pp. 230-236.
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