Evidence that specific and 'general' control of ornithine carbamoyltransferase production occurs at the level of transcription in Saccharomyces cerevisiae

F. Messenguy, Terrance Cooper

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Ornithine carbamoyltransferase synthesis is subject to 2 major regulatory systems in S. cerevisiae. One system is specific for the arginine biosynthetic enzymes, whereas the other appears to be general, acting on a variety of other amino acid pathways as well. It was observed that the synthetic capacity for continued ornithine carbamoyltransferase synthesis had the same short half life (ca. 5 to 7 min) whether repression of enzyme production was brought about by action of the specific or general control system. Evidence is presented suggesting that both control systems regulate accumulation of ornithine carbamoyltransferase specific capacity, rather than modulating its expression.

Original languageEnglish (US)
Pages (from-to)1253-1261
Number of pages9
JournalJournal of bacteriology
Volume130
Issue number3
StatePublished - Jan 1 1977

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Ornithine Carbamoyltransferase
Saccharomyces cerevisiae
Enzyme Repression
Half-Life
Arginine
Amino Acids
Enzymes

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Molecular Biology

Cite this

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