Extracranial metastases of glioblastoma in a child

Case report and review of the literature

Ali Saad, Jessica Sachs, Christopher D. Turner, Mark Proctor, Karen J. Marcus, Larry Wang, Hart Lidov, Nicole J. Ullrich

Research output: Contribution to journalReview article

25 Citations (Scopus)

Abstract

Glioblastoma (GBM) is the most common adult malignant brain tumor but is notably less common in children. Primary brain tumors rarely metastasize outside the central nervous system and when metastases occur, it is often in patients with diversionary shunting of the cerebrospinal fluid. This report details the case of a 131/2-year-old boy who was diagnosed with GBM. He survived 10 months after diagnosis. At autopsy, the tumor was found to extensively infiltrate the leptomeninges as well as the cranial skin and soft tissue. Further examination disclosed multiple liver and lung metastatic GBM nodules. This pattern of spread is very uncharacteristic of gliomas and emphasizes the importance of adequate metastatic evaluation.

Original languageEnglish (US)
Pages (from-to)190-194
Number of pages5
JournalJournal of Pediatric Hematology/Oncology
Volume29
Issue number3
DOIs
StatePublished - Mar 1 2007
Externally publishedYes

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Glioblastoma
Neoplasm Metastasis
Brain Neoplasms
Glioma
Cerebrospinal Fluid
Autopsy
Central Nervous System
Lung
Skin
Liver
Neoplasms

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

Cite this

Extracranial metastases of glioblastoma in a child : Case report and review of the literature. / Saad, Ali; Sachs, Jessica; Turner, Christopher D.; Proctor, Mark; Marcus, Karen J.; Wang, Larry; Lidov, Hart; Ullrich, Nicole J.

In: Journal of Pediatric Hematology/Oncology, Vol. 29, No. 3, 01.03.2007, p. 190-194.

Research output: Contribution to journalReview article

Saad, Ali ; Sachs, Jessica ; Turner, Christopher D. ; Proctor, Mark ; Marcus, Karen J. ; Wang, Larry ; Lidov, Hart ; Ullrich, Nicole J. / Extracranial metastases of glioblastoma in a child : Case report and review of the literature. In: Journal of Pediatric Hematology/Oncology. 2007 ; Vol. 29, No. 3. pp. 190-194.
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