F-18 fluoride positron emission tomography of the hip for osteonecrosis

Vinod Dasa, Hani Adbel-Nabi, Mark J. Anders, William Mihalko

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Osteonecrosis (ON) of the femoral head continues to be a devastating disorder for young patients. We evaluated the F-18 fluoride positron emission tomography (PET) imaging modality for use in detection of the bone involved in ON of the hip. We retrospectively reviewed the records of 60 consecutive patients diagnosed with ON and interviewed all by phone. Eleven patients (17 hips) of those interviewed agreed to participate in the study. We classified the ON using the University of Pennsylvania classification system and compared each patient's plain AP bone scan, single photon emission 3-D computed tomography, and MRI. ON was associated with HIV, alcohol, steroid use, and polycythemia vera in this group. Nine of 17 hips (8 patients) had acetabular increased uptake when using the F-18 fluoride PET scans that were not seen on MRI, single photon emission computed tomography, or bone scans. These data suggest earlier acetabular changes in osteonecrosis may exist that traditional imaging modalities do not reveal. Level of Evidence: Level III, diagnostic study. See the Guidelines for Authors for a complete description of levels of evidence.

Original languageEnglish (US)
Pages (from-to)1081-1086
Number of pages6
JournalClinical Orthopaedics and Related Research
Volume466
Issue number5
DOIs
StatePublished - Jan 1 2008
Externally publishedYes

Fingerprint

Osteonecrosis
Fluorides
Positron-Emission Tomography
Hip
Bone and Bones
Polycythemia Vera
Thigh
Single-Photon Emission-Computed Tomography
Photons
Steroids
Tomography
Alcohols
HIV
Guidelines

All Science Journal Classification (ASJC) codes

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

F-18 fluoride positron emission tomography of the hip for osteonecrosis. / Dasa, Vinod; Adbel-Nabi, Hani; Anders, Mark J.; Mihalko, William.

In: Clinical Orthopaedics and Related Research, Vol. 466, No. 5, 01.01.2008, p. 1081-1086.

Research output: Contribution to journalArticle

Dasa, Vinod ; Adbel-Nabi, Hani ; Anders, Mark J. ; Mihalko, William. / F-18 fluoride positron emission tomography of the hip for osteonecrosis. In: Clinical Orthopaedics and Related Research. 2008 ; Vol. 466, No. 5. pp. 1081-1086.
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