Fetal choroid plexus cysts

Beware the smaller cyst

M. C. Perpignano, Harris Cohen, V. R. Klein, F. S. Mandel, J. Streltzoff, F. A. Chervenak, M. A. Goldman

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Current literature suggests that amniocentesis be performed on fetuses with simple choroid plexus cysts only when such cysts are 1.0 cm or greater in diameter and bilateral. At retrospective analysis of 3,769 patients, choroid plexus cysts were noted in 87 (2.3%), representing a rate three times greater than that of previous reports. Eight-three patients underwent amniocentesis. Six (7.2%) had abnormal karyotypes. Four patients had the commonly associated chromosomal abnormality trisomy 18. Two had karyotypes not usually associated with this problem: mosaic Turner syndrome and trisomy 21. Of the six patients with abnormal karyotypes, one had a 4-mm-diameter unilateral choroid plexus cyst and three had bilateral cysts of 3-5 mm. Only one patient with a 16-mm cyst had any associated structural abnormality discovered at rigorous ultrasound examination. Karyotyping may be necessary in fetuses with small choroid plexus cysts. Deciding which patients should be encouraged to undergo amniocentesis is made more complex by these data.

Original languageEnglish (US)
Pages (from-to)715-717
Number of pages3
JournalRadiology
Volume182
Issue number3
DOIs
StatePublished - Jan 1 1992
Externally publishedYes

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Choroid Plexus
Cysts
Amniocentesis
Abnormal Karyotype
Fetus
Karyotyping
Turner Syndrome
Down Syndrome
Karyotype
Chromosome Aberrations

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Perpignano, M. C., Cohen, H., Klein, V. R., Mandel, F. S., Streltzoff, J., Chervenak, F. A., & Goldman, M. A. (1992). Fetal choroid plexus cysts: Beware the smaller cyst. Radiology, 182(3), 715-717. https://doi.org/10.1148/radiology.182.3.1535884

Fetal choroid plexus cysts : Beware the smaller cyst. / Perpignano, M. C.; Cohen, Harris; Klein, V. R.; Mandel, F. S.; Streltzoff, J.; Chervenak, F. A.; Goldman, M. A.

In: Radiology, Vol. 182, No. 3, 01.01.1992, p. 715-717.

Research output: Contribution to journalArticle

Perpignano, MC, Cohen, H, Klein, VR, Mandel, FS, Streltzoff, J, Chervenak, FA & Goldman, MA 1992, 'Fetal choroid plexus cysts: Beware the smaller cyst', Radiology, vol. 182, no. 3, pp. 715-717. https://doi.org/10.1148/radiology.182.3.1535884
Perpignano MC, Cohen H, Klein VR, Mandel FS, Streltzoff J, Chervenak FA et al. Fetal choroid plexus cysts: Beware the smaller cyst. Radiology. 1992 Jan 1;182(3):715-717. https://doi.org/10.1148/radiology.182.3.1535884
Perpignano, M. C. ; Cohen, Harris ; Klein, V. R. ; Mandel, F. S. ; Streltzoff, J. ; Chervenak, F. A. ; Goldman, M. A. / Fetal choroid plexus cysts : Beware the smaller cyst. In: Radiology. 1992 ; Vol. 182, No. 3. pp. 715-717.
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