Fetal loss after early detection of heart motion in infertility patients

Prognostic factors

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

OBJECTIVE: To evaluate the incidence and prognosticators of spontaneous abortion (< 20 weeks' gestation) in an infertile population after early documentation of fetal cardiac activity. STUDY DESIGN: Retrospective chart review. We examined the incidence of spontaneous abortion in 231 clinical pregnancies with 259 fetuses documented to be viable by transvaginal sonography 28-38 days after ovulation. The population was an unselected group of infertility patients with no history of recurrent pregnancy loss. Maternal age and presence of multiple gestations were analyzed as separate variables by X 2 testing. RESULTS: The incidence of spontaneous abortion among all fetuses was 9.6% (95% confidence interval [CI], 6.1-13.2%) and among singleton gestations was 7.7% (95% CI, 4.0-11.3%). Women with multiple gestations were more likely to suffer spontaneous fetal loss as compared to women with singleton gestations (18 vs. 7.6%, P < .05). In addition, women aged 35 and above with singleton pregnancies showed a significantly increased rate of fetal loss (13.4 vs. 4.9%, P <.05) when compared with younger women. CONCLUSION: Women ≤35 years old and those with multiple gestations were significantly more likely to suffer late first- or early second-trimester fetal loss even after detection of fetal cardiac activity. These patients should be counseled differently than younger women with singleton pregnancies, and increased monitoring may be indicated.

Original languageEnglish (US)
Pages (from-to)199-202
Number of pages4
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume43
Issue number3 SUPPL.
StatePublished - Apr 27 1998

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Infertility
Pregnancy
Spontaneous Abortion
Fetal Movement
Incidence
Fetus
Confidence Intervals
Reproductive History
Maternal Age
Second Pregnancy Trimester
Ovulation
Documentation
Population
Ultrasonography

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology

Cite this

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title = "Fetal loss after early detection of heart motion in infertility patients: Prognostic factors",
abstract = "OBJECTIVE: To evaluate the incidence and prognosticators of spontaneous abortion (< 20 weeks' gestation) in an infertile population after early documentation of fetal cardiac activity. STUDY DESIGN: Retrospective chart review. We examined the incidence of spontaneous abortion in 231 clinical pregnancies with 259 fetuses documented to be viable by transvaginal sonography 28-38 days after ovulation. The population was an unselected group of infertility patients with no history of recurrent pregnancy loss. Maternal age and presence of multiple gestations were analyzed as separate variables by X 2 testing. RESULTS: The incidence of spontaneous abortion among all fetuses was 9.6{\%} (95{\%} confidence interval [CI], 6.1-13.2{\%}) and among singleton gestations was 7.7{\%} (95{\%} CI, 4.0-11.3{\%}). Women with multiple gestations were more likely to suffer spontaneous fetal loss as compared to women with singleton gestations (18 vs. 7.6{\%}, P < .05). In addition, women aged 35 and above with singleton pregnancies showed a significantly increased rate of fetal loss (13.4 vs. 4.9{\%}, P <.05) when compared with younger women. CONCLUSION: Women ≤35 years old and those with multiple gestations were significantly more likely to suffer late first- or early second-trimester fetal loss even after detection of fetal cardiac activity. These patients should be counseled differently than younger women with singleton pregnancies, and increased monitoring may be indicated.",
author = "Jeffrey Keenan and S. Rizvi and Michael Caudle",
year = "1998",
month = "4",
day = "27",
language = "English (US)",
volume = "43",
pages = "199--202",
journal = "The Journal of reproductive medicine",
issn = "0024-7758",
publisher = "Donna Kessel",
number = "3 SUPPL.",

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TY - JOUR

T1 - Fetal loss after early detection of heart motion in infertility patients

T2 - Prognostic factors

AU - Keenan, Jeffrey

AU - Rizvi, S.

AU - Caudle, Michael

PY - 1998/4/27

Y1 - 1998/4/27

N2 - OBJECTIVE: To evaluate the incidence and prognosticators of spontaneous abortion (< 20 weeks' gestation) in an infertile population after early documentation of fetal cardiac activity. STUDY DESIGN: Retrospective chart review. We examined the incidence of spontaneous abortion in 231 clinical pregnancies with 259 fetuses documented to be viable by transvaginal sonography 28-38 days after ovulation. The population was an unselected group of infertility patients with no history of recurrent pregnancy loss. Maternal age and presence of multiple gestations were analyzed as separate variables by X 2 testing. RESULTS: The incidence of spontaneous abortion among all fetuses was 9.6% (95% confidence interval [CI], 6.1-13.2%) and among singleton gestations was 7.7% (95% CI, 4.0-11.3%). Women with multiple gestations were more likely to suffer spontaneous fetal loss as compared to women with singleton gestations (18 vs. 7.6%, P < .05). In addition, women aged 35 and above with singleton pregnancies showed a significantly increased rate of fetal loss (13.4 vs. 4.9%, P <.05) when compared with younger women. CONCLUSION: Women ≤35 years old and those with multiple gestations were significantly more likely to suffer late first- or early second-trimester fetal loss even after detection of fetal cardiac activity. These patients should be counseled differently than younger women with singleton pregnancies, and increased monitoring may be indicated.

AB - OBJECTIVE: To evaluate the incidence and prognosticators of spontaneous abortion (< 20 weeks' gestation) in an infertile population after early documentation of fetal cardiac activity. STUDY DESIGN: Retrospective chart review. We examined the incidence of spontaneous abortion in 231 clinical pregnancies with 259 fetuses documented to be viable by transvaginal sonography 28-38 days after ovulation. The population was an unselected group of infertility patients with no history of recurrent pregnancy loss. Maternal age and presence of multiple gestations were analyzed as separate variables by X 2 testing. RESULTS: The incidence of spontaneous abortion among all fetuses was 9.6% (95% confidence interval [CI], 6.1-13.2%) and among singleton gestations was 7.7% (95% CI, 4.0-11.3%). Women with multiple gestations were more likely to suffer spontaneous fetal loss as compared to women with singleton gestations (18 vs. 7.6%, P < .05). In addition, women aged 35 and above with singleton pregnancies showed a significantly increased rate of fetal loss (13.4 vs. 4.9%, P <.05) when compared with younger women. CONCLUSION: Women ≤35 years old and those with multiple gestations were significantly more likely to suffer late first- or early second-trimester fetal loss even after detection of fetal cardiac activity. These patients should be counseled differently than younger women with singleton pregnancies, and increased monitoring may be indicated.

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