Fine needle aspiration cytologic findings of micropapillary carcinoma in the lung

A case report

Lisa Duncan, Sanjivini Jacob, Steven Atkinson

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Micropapillary carcinoma is a variant of adenocarcinoma described in many anatomic sites and most recently in the lung. The cytologic recognition of this distinct pathologic entity in transthoracic needle aspiration specimens is important in providing prognostic information and therapeutic guidance. Case: A 58-year-old woman presented with a < 1-cm lesion in the left breast identified on screening mammogram. A core biopsy of this lesion revealed an estrogen and progesterone receptor positive tubular carcinoma. Before a hookwire localization biopsy, a chest x-ray revealed a 1.7-cm spiculated mass in the right lower lobe. The diagnosis of adenocarcinoma with micropapillary features was made by fine needle aspiration cytology (FNAC). The lobectomy specimen showed a combination of adenocarcinoma, papillary adenocarcinoma and micropapdlary carcinoma. Conclusion: Micropapillary carcinoma is a unique variant of adenocarcinoma, having important clinical associations because of its propensity for angiolymphatic invasion and higher stage at disease presentation. This case demonstrates the cytomorphologic characteristics of micropapillary carcinoma in a transthoracic FNA of the lung.

Original languageEnglish (US)
Pages (from-to)605-609
Number of pages5
JournalActa Cytologica
Volume51
Issue number4
DOIs
StatePublished - Jan 1 2007

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Fine Needle Biopsy
Adenocarcinoma
Carcinoma
Lung
Papillary Adenocarcinoma
Biopsy
Progesterone Receptors
Estrogen Receptors
Needles
Cell Biology
Breast
Thorax
X-Rays
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology

Cite this

Fine needle aspiration cytologic findings of micropapillary carcinoma in the lung : A case report. / Duncan, Lisa; Jacob, Sanjivini; Atkinson, Steven.

In: Acta Cytologica, Vol. 51, No. 4, 01.01.2007, p. 605-609.

Research output: Contribution to journalArticle

Duncan, Lisa ; Jacob, Sanjivini ; Atkinson, Steven. / Fine needle aspiration cytologic findings of micropapillary carcinoma in the lung : A case report. In: Acta Cytologica. 2007 ; Vol. 51, No. 4. pp. 605-609.
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