Five-year group A streptococcal pharyngitis serotype surveillance in North America, 2000-2005

Robert R. Tanz, Stanford T. Shulman, William Kabat, Kathleen Kabat, Emily Cederlund, Devendra Patel, Zhongya Li, Varja Sakota, James Dale, Bernard Beall

Research output: Contribution to journalArticle

Abstract

The geographic and year-year heterogeneity of group A streptococcal (GAS) genotypes (emm types) of isolates causing acute pediatric pharyngitis in North America have been poorly characterized. We established a network of 10 U.S. and 3 Canadian sites to collect isolates from children 3-18 years old with acute streptococcal pharyngitis. Collection began in 2000-2001, and the fifth year of collection was completed in May 2005. Multiple GAS types circulated simultaneously within each study site. Each year the 3 most prevalent emm types in the U.S. or Canada comprised 42-49% of all isolates nationally. The 6 most prevalent types each year consistently comprised 70-77% of isolates. Analysis of data from individual sites demonstrated considerable (in some instances striking) geographic variability as well as year-year variability. Differences were identified between the distribution of emm types from U.S. and Canadian sites. Continued pharyngeal emm type surveillance will be needed as multivalent M protein vaccine development proceeds.

Original languageEnglish (US)
Pages (from-to)30-33
Number of pages4
JournalInternational Congress Series
Volume1289
DOIs
StatePublished - Apr 1 2006

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Pharyngitis
North America
Canada
Vaccines
Genotype
Pediatrics
Proteins
Serogroup

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Tanz, R. R., Shulman, S. T., Kabat, W., Kabat, K., Cederlund, E., Patel, D., ... Beall, B. (2006). Five-year group A streptococcal pharyngitis serotype surveillance in North America, 2000-2005. International Congress Series, 1289, 30-33. https://doi.org/10.1016/j.ics.2005.09.089

Five-year group A streptococcal pharyngitis serotype surveillance in North America, 2000-2005. / Tanz, Robert R.; Shulman, Stanford T.; Kabat, William; Kabat, Kathleen; Cederlund, Emily; Patel, Devendra; Li, Zhongya; Sakota, Varja; Dale, James; Beall, Bernard.

In: International Congress Series, Vol. 1289, 01.04.2006, p. 30-33.

Research output: Contribution to journalArticle

Tanz, RR, Shulman, ST, Kabat, W, Kabat, K, Cederlund, E, Patel, D, Li, Z, Sakota, V, Dale, J & Beall, B 2006, 'Five-year group A streptococcal pharyngitis serotype surveillance in North America, 2000-2005', International Congress Series, vol. 1289, pp. 30-33. https://doi.org/10.1016/j.ics.2005.09.089
Tanz, Robert R. ; Shulman, Stanford T. ; Kabat, William ; Kabat, Kathleen ; Cederlund, Emily ; Patel, Devendra ; Li, Zhongya ; Sakota, Varja ; Dale, James ; Beall, Bernard. / Five-year group A streptococcal pharyngitis serotype surveillance in North America, 2000-2005. In: International Congress Series. 2006 ; Vol. 1289. pp. 30-33.
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