Flow velocity waveforms of the vascular system in the anemic fetus before and after intravascular transfusion for severe red blood cell alloimmunization

Giancarlo Mari, Kenneth J. Moise, Russell L. Deter, Brian Kirshon, Theodor Stefos, Robert J. Carpenter

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Sixteen intravascular transfusions were performed in 16 anemic human fetuses. To investigate the status of the vascular system with Doppler ultrasonography before and after correction of anemia, pulsatility index values were obtained for the flow velocity waveforms of the middle cerebral artery, internal carotid artery, anterior cerebral artery, thoracic aorta, abdominal aorta, renal artery, femoral artery, and umbilical artery before and the day after the correction of anemia. The fetuses were divided into two groups: (1) fetuses with a hematocrit level between 2 and 4 SDs below the normal mean value for gestational age and (2) fetuses with a hematocrit value < 4 SDs below the normal mean value for gestational age. No significant differences were observed in the pulsatility index values of the vessels studied before and after correction of anemia in both groups of fetuses. These data suggest that the pulsatility index cannot be used as an indicator of fetal anemia at the hematocrit values studied.

Original languageEnglish (US)
Pages (from-to)1060-1064
Number of pages5
JournalAmerican Journal of Obstetrics and Gynecology
Volume162
Issue number4
DOIs
StatePublished - Jan 1 1990
Externally publishedYes

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Erythrocyte Transfusion
Blood Vessels
Fetus
Anemia
Hematocrit
Gestational Age
Reference Values
Anterior Cerebral Artery
Doppler Ultrasonography
Umbilical Arteries
Abdominal Aorta
Middle Cerebral Artery
Internal Carotid Artery
Renal Artery
Femoral Artery
Thoracic Aorta

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

Cite this

Flow velocity waveforms of the vascular system in the anemic fetus before and after intravascular transfusion for severe red blood cell alloimmunization. / Mari, Giancarlo; Moise, Kenneth J.; Deter, Russell L.; Kirshon, Brian; Stefos, Theodor; Carpenter, Robert J.

In: American Journal of Obstetrics and Gynecology, Vol. 162, No. 4, 01.01.1990, p. 1060-1064.

Research output: Contribution to journalArticle

Mari, Giancarlo ; Moise, Kenneth J. ; Deter, Russell L. ; Kirshon, Brian ; Stefos, Theodor ; Carpenter, Robert J. / Flow velocity waveforms of the vascular system in the anemic fetus before and after intravascular transfusion for severe red blood cell alloimmunization. In: American Journal of Obstetrics and Gynecology. 1990 ; Vol. 162, No. 4. pp. 1060-1064.
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