Fluconazole-carbamazepine interaction

Christopher K. Finch, Christie A. Green, Timothy H. Self

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The patient we describe had elevated carbamazepine serum concentrations during concomitant fluconazole administration (400 mg/day), including serial concentrations both before and after antifungal therapy. Since fluconazole is a known inhibitor of the cytochrome P-450 enzyme system, this suggests an inhibition of carbamazepine metabolism.

Original languageEnglish (US)
Pages (from-to)1099-1100
Number of pages2
JournalSouthern Medical Journal
Volume95
Issue number9
StatePublished - Sep 1 2002

Fingerprint

Fluconazole
Carbamazepine
Cytochrome P-450 Enzyme System
Serum
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Finch, C. K., Green, C. A., & Self, T. H. (2002). Fluconazole-carbamazepine interaction. Southern Medical Journal, 95(9), 1099-1100.

Fluconazole-carbamazepine interaction. / Finch, Christopher K.; Green, Christie A.; Self, Timothy H.

In: Southern Medical Journal, Vol. 95, No. 9, 01.09.2002, p. 1099-1100.

Research output: Contribution to journalArticle

Finch, CK, Green, CA & Self, TH 2002, 'Fluconazole-carbamazepine interaction', Southern Medical Journal, vol. 95, no. 9, pp. 1099-1100.
Finch CK, Green CA, Self TH. Fluconazole-carbamazepine interaction. Southern Medical Journal. 2002 Sep 1;95(9):1099-1100.
Finch, Christopher K. ; Green, Christie A. ; Self, Timothy H. / Fluconazole-carbamazepine interaction. In: Southern Medical Journal. 2002 ; Vol. 95, No. 9. pp. 1099-1100.
@article{aa3755bdc67e4888ae7b6b33db9ea06c,
title = "Fluconazole-carbamazepine interaction",
abstract = "The patient we describe had elevated carbamazepine serum concentrations during concomitant fluconazole administration (400 mg/day), including serial concentrations both before and after antifungal therapy. Since fluconazole is a known inhibitor of the cytochrome P-450 enzyme system, this suggests an inhibition of carbamazepine metabolism.",
author = "Finch, {Christopher K.} and Green, {Christie A.} and Self, {Timothy H.}",
year = "2002",
month = "9",
day = "1",
language = "English (US)",
volume = "95",
pages = "1099--1100",
journal = "Southern Medical Journal",
issn = "0038-4348",
publisher = "Lippincott Williams and Wilkins",
number = "9",

}

TY - JOUR

T1 - Fluconazole-carbamazepine interaction

AU - Finch, Christopher K.

AU - Green, Christie A.

AU - Self, Timothy H.

PY - 2002/9/1

Y1 - 2002/9/1

N2 - The patient we describe had elevated carbamazepine serum concentrations during concomitant fluconazole administration (400 mg/day), including serial concentrations both before and after antifungal therapy. Since fluconazole is a known inhibitor of the cytochrome P-450 enzyme system, this suggests an inhibition of carbamazepine metabolism.

AB - The patient we describe had elevated carbamazepine serum concentrations during concomitant fluconazole administration (400 mg/day), including serial concentrations both before and after antifungal therapy. Since fluconazole is a known inhibitor of the cytochrome P-450 enzyme system, this suggests an inhibition of carbamazepine metabolism.

UR - http://www.scopus.com/inward/record.url?scp=0036734592&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036734592&partnerID=8YFLogxK

M3 - Article

VL - 95

SP - 1099

EP - 1100

JO - Southern Medical Journal

JF - Southern Medical Journal

SN - 0038-4348

IS - 9

ER -