Fluoride content in breast milk after the use of fluoridated food supplement. A randomized clinical trial

Guglielmo Campus, Giovanna Congiu, Fabio Cocco, Silvana Sale, Maria Grazia Cagetti, Gavino Sanna, Peter Lingström, Franklin Garcia-Godoy

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Purpose: To evaluate if the intake of a fluoridated food supplement in breastfeeding mothers increases the fluoride concentration in breast milk. Methods: A double-blind randomized placebo-controlled study was designed. Two groups of women were formed: a fluoride group (n=l 12), using a non-sucrose food supplement containing fluoride (1,500 μg/1 for each dose) and a control group (n=l 16), using a non-sucrose food supplement without fluoride content. The women were followed for 6 weeks. Samples of breast milk were collected and analyzed using an ion-specific electrode.

Results: 85 women in the fluoride group and 83 in the control group concluded the trial. Fluoride concentrations in the two groups were statistically significantly different (515 μg/1 in the fluoride and 476 μg/1 in the control group P= 0.04) at the end of the experimental period. In the fluoride group, a statistically significant increment in fluoride concentration during the experimental period was also observed (from 468±104 μg/1 to 515± 105 μg/1). The use of a non-sucrose food supplement containing fluoride resulted in a significant increment in fluoride concentration in breast milk.

Original languageEnglish (US)
Pages (from-to)199-202
Number of pages4
JournalAmerican Journal of Dentistry
Volume27
Issue number4
StatePublished - Jan 1 2014

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Human Milk
Dietary Supplements
Fluorides
Randomized Controlled Trials
Control Groups
Breast Feeding
Double-Blind Method
Electrodes
Placebos
Mothers
Ions

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Dentistry(all)

Cite this

Fluoride content in breast milk after the use of fluoridated food supplement. A randomized clinical trial. / Campus, Guglielmo; Congiu, Giovanna; Cocco, Fabio; Sale, Silvana; Cagetti, Maria Grazia; Sanna, Gavino; Lingström, Peter; Garcia-Godoy, Franklin.

In: American Journal of Dentistry, Vol. 27, No. 4, 01.01.2014, p. 199-202.

Research output: Contribution to journalArticle

Campus, G, Congiu, G, Cocco, F, Sale, S, Cagetti, MG, Sanna, G, Lingström, P & Garcia-Godoy, F 2014, 'Fluoride content in breast milk after the use of fluoridated food supplement. A randomized clinical trial', American Journal of Dentistry, vol. 27, no. 4, pp. 199-202.
Campus G, Congiu G, Cocco F, Sale S, Cagetti MG, Sanna G et al. Fluoride content in breast milk after the use of fluoridated food supplement. A randomized clinical trial. American Journal of Dentistry. 2014 Jan 1;27(4):199-202.
Campus, Guglielmo ; Congiu, Giovanna ; Cocco, Fabio ; Sale, Silvana ; Cagetti, Maria Grazia ; Sanna, Gavino ; Lingström, Peter ; Garcia-Godoy, Franklin. / Fluoride content in breast milk after the use of fluoridated food supplement. A randomized clinical trial. In: American Journal of Dentistry. 2014 ; Vol. 27, No. 4. pp. 199-202.
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AU - Lingström, Peter

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N2 - Purpose: To evaluate if the intake of a fluoridated food supplement in breastfeeding mothers increases the fluoride concentration in breast milk. Methods: A double-blind randomized placebo-controlled study was designed. Two groups of women were formed: a fluoride group (n=l 12), using a non-sucrose food supplement containing fluoride (1,500 μg/1 for each dose) and a control group (n=l 16), using a non-sucrose food supplement without fluoride content. The women were followed for 6 weeks. Samples of breast milk were collected and analyzed using an ion-specific electrode.Results: 85 women in the fluoride group and 83 in the control group concluded the trial. Fluoride concentrations in the two groups were statistically significantly different (515 μg/1 in the fluoride and 476 μg/1 in the control group P= 0.04) at the end of the experimental period. In the fluoride group, a statistically significant increment in fluoride concentration during the experimental period was also observed (from 468±104 μg/1 to 515± 105 μg/1). The use of a non-sucrose food supplement containing fluoride resulted in a significant increment in fluoride concentration in breast milk.

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