Fluoride uptake by human tooth enamel

Topical application versus combined dielectrophoresis and AC electroosmosis

Research output: Contribution to journalArticle

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Abstract

Purpose: To compare fluoride uptake by enamel after applying 1.23% acidulated phosphate fluoride gel to human tooth enamel topically (n=12) or with combined dielectrophoresis and AC electroosmosis (DEP/ACE) at frequencies of 10, 400 and 5,000 Hz (n=12) for 20 minutes. Methods: DEP/ACE induced nonuniform electrical fields with three alternating current frequencies to polarize, orient, and motivate fluoride particles. Fluoride concentrations were measured at various enamel depths using wavelength dispersive spectrometry. Data were analyzed by ANOVA/Student-Newman-Keuls post hoc tests (P≤ 0.05). Results: Fluoride concentrations in the diffusion group were significantly higher than baseline readings at 10, 20 and 50 μm depths. Fluoride concentrations in DEP/ACE-treated teeth were significantly higher than the diffusion group at 10, 20, 50, 100, 200 and 300 μm (ANOVA/Student-Newman-Keuls post hoc, P< 0.05). Fluoride uptake with DEP/ACE was substantially higher than diffusion at 10,20, 50, 100, 200 and 300 μm depths (paired t test, P< 0.05). DEP/ACE transported fluoride up to 300 μm deep, whereas conventional fluoride application was comparatively ineffective beyond 20 μm depth (P< 0.05). Compared to passive diffusion, fluoride uptake in enamel was significantly higher in the DEP/ACE group at 10, 20, 50, 100, 200 and 300 μm depths (P< 0.05). DEP/ACE drove fluoride substantially deeper into human enamel with a difference in uptake 1,575 ppm higher than diffusion at 100 μ depth; 6 times higher at 50 μm depth; 5 times higher at 20 μm depth; and 7 times higher at 10 μm depth. Fluoride levels at 100 μ were equivalent to long-term prophylactic exposure.

Original languageEnglish (US)
Pages (from-to)166-172
Number of pages7
JournalAmerican journal of dentistry
Volume26
Issue number3
StatePublished - Jun 1 2013

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Electroosmosis
Dental Enamel
Fluorides
Tooth
Analysis of Variance
Acidulated Phosphate Fluoride
Students
Reading
Spectrum Analysis

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Cite this

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title = "Fluoride uptake by human tooth enamel: Topical application versus combined dielectrophoresis and AC electroosmosis",
abstract = "Purpose: To compare fluoride uptake by enamel after applying 1.23{\%} acidulated phosphate fluoride gel to human tooth enamel topically (n=12) or with combined dielectrophoresis and AC electroosmosis (DEP/ACE) at frequencies of 10, 400 and 5,000 Hz (n=12) for 20 minutes. Methods: DEP/ACE induced nonuniform electrical fields with three alternating current frequencies to polarize, orient, and motivate fluoride particles. Fluoride concentrations were measured at various enamel depths using wavelength dispersive spectrometry. Data were analyzed by ANOVA/Student-Newman-Keuls post hoc tests (P≤ 0.05). Results: Fluoride concentrations in the diffusion group were significantly higher than baseline readings at 10, 20 and 50 μm depths. Fluoride concentrations in DEP/ACE-treated teeth were significantly higher than the diffusion group at 10, 20, 50, 100, 200 and 300 μm (ANOVA/Student-Newman-Keuls post hoc, P< 0.05). Fluoride uptake with DEP/ACE was substantially higher than diffusion at 10,20, 50, 100, 200 and 300 μm depths (paired t test, P< 0.05). DEP/ACE transported fluoride up to 300 μm deep, whereas conventional fluoride application was comparatively ineffective beyond 20 μm depth (P< 0.05). Compared to passive diffusion, fluoride uptake in enamel was significantly higher in the DEP/ACE group at 10, 20, 50, 100, 200 and 300 μm depths (P< 0.05). DEP/ACE drove fluoride substantially deeper into human enamel with a difference in uptake 1,575 ppm higher than diffusion at 100 μ depth; 6 times higher at 50 μm depth; 5 times higher at 20 μm depth; and 7 times higher at 10 μm depth. Fluoride levels at 100 μ were equivalent to long-term prophylactic exposure.",
author = "Chris Ivanoff and Morshed, {Bashir I.} and Timothy Hottel and Franklin Garcia-Godoy",
year = "2013",
month = "6",
day = "1",
language = "English (US)",
volume = "26",
pages = "166--172",
journal = "American Journal of Dentistry",
issn = "0894-8275",
publisher = "Mosher and Linder, Inc",
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TY - JOUR

T1 - Fluoride uptake by human tooth enamel

T2 - Topical application versus combined dielectrophoresis and AC electroosmosis

AU - Ivanoff, Chris

AU - Morshed, Bashir I.

AU - Hottel, Timothy

AU - Garcia-Godoy, Franklin

PY - 2013/6/1

Y1 - 2013/6/1

N2 - Purpose: To compare fluoride uptake by enamel after applying 1.23% acidulated phosphate fluoride gel to human tooth enamel topically (n=12) or with combined dielectrophoresis and AC electroosmosis (DEP/ACE) at frequencies of 10, 400 and 5,000 Hz (n=12) for 20 minutes. Methods: DEP/ACE induced nonuniform electrical fields with three alternating current frequencies to polarize, orient, and motivate fluoride particles. Fluoride concentrations were measured at various enamel depths using wavelength dispersive spectrometry. Data were analyzed by ANOVA/Student-Newman-Keuls post hoc tests (P≤ 0.05). Results: Fluoride concentrations in the diffusion group were significantly higher than baseline readings at 10, 20 and 50 μm depths. Fluoride concentrations in DEP/ACE-treated teeth were significantly higher than the diffusion group at 10, 20, 50, 100, 200 and 300 μm (ANOVA/Student-Newman-Keuls post hoc, P< 0.05). Fluoride uptake with DEP/ACE was substantially higher than diffusion at 10,20, 50, 100, 200 and 300 μm depths (paired t test, P< 0.05). DEP/ACE transported fluoride up to 300 μm deep, whereas conventional fluoride application was comparatively ineffective beyond 20 μm depth (P< 0.05). Compared to passive diffusion, fluoride uptake in enamel was significantly higher in the DEP/ACE group at 10, 20, 50, 100, 200 and 300 μm depths (P< 0.05). DEP/ACE drove fluoride substantially deeper into human enamel with a difference in uptake 1,575 ppm higher than diffusion at 100 μ depth; 6 times higher at 50 μm depth; 5 times higher at 20 μm depth; and 7 times higher at 10 μm depth. Fluoride levels at 100 μ were equivalent to long-term prophylactic exposure.

AB - Purpose: To compare fluoride uptake by enamel after applying 1.23% acidulated phosphate fluoride gel to human tooth enamel topically (n=12) or with combined dielectrophoresis and AC electroosmosis (DEP/ACE) at frequencies of 10, 400 and 5,000 Hz (n=12) for 20 minutes. Methods: DEP/ACE induced nonuniform electrical fields with three alternating current frequencies to polarize, orient, and motivate fluoride particles. Fluoride concentrations were measured at various enamel depths using wavelength dispersive spectrometry. Data were analyzed by ANOVA/Student-Newman-Keuls post hoc tests (P≤ 0.05). Results: Fluoride concentrations in the diffusion group were significantly higher than baseline readings at 10, 20 and 50 μm depths. Fluoride concentrations in DEP/ACE-treated teeth were significantly higher than the diffusion group at 10, 20, 50, 100, 200 and 300 μm (ANOVA/Student-Newman-Keuls post hoc, P< 0.05). Fluoride uptake with DEP/ACE was substantially higher than diffusion at 10,20, 50, 100, 200 and 300 μm depths (paired t test, P< 0.05). DEP/ACE transported fluoride up to 300 μm deep, whereas conventional fluoride application was comparatively ineffective beyond 20 μm depth (P< 0.05). Compared to passive diffusion, fluoride uptake in enamel was significantly higher in the DEP/ACE group at 10, 20, 50, 100, 200 and 300 μm depths (P< 0.05). DEP/ACE drove fluoride substantially deeper into human enamel with a difference in uptake 1,575 ppm higher than diffusion at 100 μ depth; 6 times higher at 50 μm depth; 5 times higher at 20 μm depth; and 7 times higher at 10 μm depth. Fluoride levels at 100 μ were equivalent to long-term prophylactic exposure.

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M3 - Article

VL - 26

SP - 166

EP - 172

JO - American Journal of Dentistry

JF - American Journal of Dentistry

SN - 0894-8275

IS - 3

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