Focal nodular hyperplasia

Central scar enhancement pattern using gadoxetate disodium

Adib R. Karam, Sridhar Shankar, Padmaja Surapaneni, Young H. Kim, Sarwat Hussain

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Purpose: To illustrate the unusual enhancement pattern of the focal nodular hyperplasia central scar using Gadoxetate Disodium. Materials and Methods: Over a 10-month period, six patients, with a total of seven focal nodular hyperplasia lesions with typical central scar, had MRI of the liver using Gadoxetate Disodium (Eovist, Bayer HealthCare Pharmaceuticals Inc., Wayne, NJ). Four of the six patients had a prior Gadobenate Dimeglumine (Multihance, Bracco Diagnostics Inc., Princeton, NJ) -enhanced MRI of the liver performed within the previous year. The dynamic enhancement pattern of the central scar on the 10 liver MRIs was independently analyzed by two abdominal imaging radiologists who were blinded to the contrast agent used. Results: On the Gadoxetate Disodium-enhanced MRIs and during the arterial phase, 1-min, 2-min, and 3-min delay, none of the central scars demonstrated enhancement. However, all four of the lesions that were previously scanned using Gadobenate Dimeglumine demonstrated typical enhancement after a 3-min delay. Conclusion: On Gadoxetate Disodium-enhanced MRIs of the liver, the central scar of focal nodular hyperplasia lesions does not typically demonstrate delayed enhancement.

Original languageEnglish (US)
Pages (from-to)341-344
Number of pages4
JournalJournal of Magnetic Resonance Imaging
Volume32
Issue number2
DOIs
StatePublished - Aug 1 2010

Fingerprint

Focal Nodular Hyperplasia
Cicatrix
Liver
Contrast Media
gadolinium ethoxybenzyl DTPA
Delivery of Health Care
Pharmaceutical Preparations
gadobenic acid

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Focal nodular hyperplasia : Central scar enhancement pattern using gadoxetate disodium. / Karam, Adib R.; Shankar, Sridhar; Surapaneni, Padmaja; Kim, Young H.; Hussain, Sarwat.

In: Journal of Magnetic Resonance Imaging, Vol. 32, No. 2, 01.08.2010, p. 341-344.

Research output: Contribution to journalArticle

Karam, Adib R. ; Shankar, Sridhar ; Surapaneni, Padmaja ; Kim, Young H. ; Hussain, Sarwat. / Focal nodular hyperplasia : Central scar enhancement pattern using gadoxetate disodium. In: Journal of Magnetic Resonance Imaging. 2010 ; Vol. 32, No. 2. pp. 341-344.
@article{ba69ca5d8f094ce2a3776f182d17f657,
title = "Focal nodular hyperplasia: Central scar enhancement pattern using gadoxetate disodium",
abstract = "Purpose: To illustrate the unusual enhancement pattern of the focal nodular hyperplasia central scar using Gadoxetate Disodium. Materials and Methods: Over a 10-month period, six patients, with a total of seven focal nodular hyperplasia lesions with typical central scar, had MRI of the liver using Gadoxetate Disodium (Eovist, Bayer HealthCare Pharmaceuticals Inc., Wayne, NJ). Four of the six patients had a prior Gadobenate Dimeglumine (Multihance, Bracco Diagnostics Inc., Princeton, NJ) -enhanced MRI of the liver performed within the previous year. The dynamic enhancement pattern of the central scar on the 10 liver MRIs was independently analyzed by two abdominal imaging radiologists who were blinded to the contrast agent used. Results: On the Gadoxetate Disodium-enhanced MRIs and during the arterial phase, 1-min, 2-min, and 3-min delay, none of the central scars demonstrated enhancement. However, all four of the lesions that were previously scanned using Gadobenate Dimeglumine demonstrated typical enhancement after a 3-min delay. Conclusion: On Gadoxetate Disodium-enhanced MRIs of the liver, the central scar of focal nodular hyperplasia lesions does not typically demonstrate delayed enhancement.",
author = "Karam, {Adib R.} and Sridhar Shankar and Padmaja Surapaneni and Kim, {Young H.} and Sarwat Hussain",
year = "2010",
month = "8",
day = "1",
doi = "10.1002/jmri.22262",
language = "English (US)",
volume = "32",
pages = "341--344",
journal = "Journal of Magnetic Resonance Imaging",
issn = "1053-1807",
publisher = "John Wiley and Sons Inc.",
number = "2",

}

TY - JOUR

T1 - Focal nodular hyperplasia

T2 - Central scar enhancement pattern using gadoxetate disodium

AU - Karam, Adib R.

AU - Shankar, Sridhar

AU - Surapaneni, Padmaja

AU - Kim, Young H.

AU - Hussain, Sarwat

PY - 2010/8/1

Y1 - 2010/8/1

N2 - Purpose: To illustrate the unusual enhancement pattern of the focal nodular hyperplasia central scar using Gadoxetate Disodium. Materials and Methods: Over a 10-month period, six patients, with a total of seven focal nodular hyperplasia lesions with typical central scar, had MRI of the liver using Gadoxetate Disodium (Eovist, Bayer HealthCare Pharmaceuticals Inc., Wayne, NJ). Four of the six patients had a prior Gadobenate Dimeglumine (Multihance, Bracco Diagnostics Inc., Princeton, NJ) -enhanced MRI of the liver performed within the previous year. The dynamic enhancement pattern of the central scar on the 10 liver MRIs was independently analyzed by two abdominal imaging radiologists who were blinded to the contrast agent used. Results: On the Gadoxetate Disodium-enhanced MRIs and during the arterial phase, 1-min, 2-min, and 3-min delay, none of the central scars demonstrated enhancement. However, all four of the lesions that were previously scanned using Gadobenate Dimeglumine demonstrated typical enhancement after a 3-min delay. Conclusion: On Gadoxetate Disodium-enhanced MRIs of the liver, the central scar of focal nodular hyperplasia lesions does not typically demonstrate delayed enhancement.

AB - Purpose: To illustrate the unusual enhancement pattern of the focal nodular hyperplasia central scar using Gadoxetate Disodium. Materials and Methods: Over a 10-month period, six patients, with a total of seven focal nodular hyperplasia lesions with typical central scar, had MRI of the liver using Gadoxetate Disodium (Eovist, Bayer HealthCare Pharmaceuticals Inc., Wayne, NJ). Four of the six patients had a prior Gadobenate Dimeglumine (Multihance, Bracco Diagnostics Inc., Princeton, NJ) -enhanced MRI of the liver performed within the previous year. The dynamic enhancement pattern of the central scar on the 10 liver MRIs was independently analyzed by two abdominal imaging radiologists who were blinded to the contrast agent used. Results: On the Gadoxetate Disodium-enhanced MRIs and during the arterial phase, 1-min, 2-min, and 3-min delay, none of the central scars demonstrated enhancement. However, all four of the lesions that were previously scanned using Gadobenate Dimeglumine demonstrated typical enhancement after a 3-min delay. Conclusion: On Gadoxetate Disodium-enhanced MRIs of the liver, the central scar of focal nodular hyperplasia lesions does not typically demonstrate delayed enhancement.

UR - http://www.scopus.com/inward/record.url?scp=77955355829&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77955355829&partnerID=8YFLogxK

U2 - 10.1002/jmri.22262

DO - 10.1002/jmri.22262

M3 - Article

VL - 32

SP - 341

EP - 344

JO - Journal of Magnetic Resonance Imaging

JF - Journal of Magnetic Resonance Imaging

SN - 1053-1807

IS - 2

ER -