Formation of calcium-parvalbumin complex during contraction. A source of "unexplained heat"?

J. M. Gillis, Donald Thomason, J. Lefevre, R. H. Kretsinger

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Computer simulation of the kinetics of the distribution of Ca between troponin, parvalbumin and the sarcoplasmic reticulum, during contraction and relaxation shows that parvalbumins can contribute significantly to the rate of relaxation and to the post contractile translocation of calcium. The binding of Ca to parvalbumin is an exothermic process which may account for about 20% of the 'unexplained heat' during contraction.

Original languageEnglish (US)
Pages (from-to)573-579
Number of pages7
JournalAdvances in Experimental Medicine and Biology
Volume170
StatePublished - 1984
Externally publishedYes

Fingerprint

Parvalbumins
Hot Temperature
Calcium
Troponin
Sarcoplasmic Reticulum
Computer Simulation
Kinetics
Computer simulation

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Formation of calcium-parvalbumin complex during contraction. A source of "unexplained heat"? / Gillis, J. M.; Thomason, Donald; Lefevre, J.; Kretsinger, R. H.

In: Advances in Experimental Medicine and Biology, Vol. 170, 1984, p. 573-579.

Research output: Contribution to journalArticle

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