Functional hemispheric asymmetry assessment in a visual language task using MEG

George Zouridakis, Panagiotis G. Simos, Joshua I. Breier, Andrew Papanicolaou

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

We used magnetoencephalography (MEG) to assess the degree of hemispheric activation in eleven normal, right-handed subjects with no history of neurological disorder or learning disability during performance of a word- and a face-recognition tasks. Neuromagnetic activity was recorded using a whole-head system, and the sources of the recorded magnetic fields were modeled as single equivalent current dipoles. Early (< 200 msec) cerebral activation, defined by the number of dipoles identified by the data-fitting algorithm, was localized in the occipital cortex during both tasks, as expected. During the language task, the extent of the later (> 200 msec) cerebral activation was approximately double in the left hemisphere in almost all subjects, involving temporal and temporoparietal areas. In contrast, during the face-recognition task, the corresponding activation was mostly symmetrical across the two occipital lobes, also involving the posterior-inferior aspect of the right temporal lobe. Our results suggest that the MEG is a suitable method of assessing noninvasively hemispheric specialization for language.

Original languageEnglish (US)
Pages (from-to)57-65
Number of pages9
JournalBrain Topography
Volume11
Issue number1
DOIs
StatePublished - Oct 19 1998

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Magnetoencephalography
Language
Cerebral Dominance
Occipital Lobe
Learning Disorders
Temporal Lobe
Magnetic Fields
Nervous System Diseases
Head
Facial Recognition

All Science Journal Classification (ASJC) codes

  • Anatomy
  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Clinical Neurology

Cite this

Zouridakis, G., Simos, P. G., Breier, J. I., & Papanicolaou, A. (1998). Functional hemispheric asymmetry assessment in a visual language task using MEG. Brain Topography, 11(1), 57-65. https://doi.org/10.1023/A:1022270620396

Functional hemispheric asymmetry assessment in a visual language task using MEG. / Zouridakis, George; Simos, Panagiotis G.; Breier, Joshua I.; Papanicolaou, Andrew.

In: Brain Topography, Vol. 11, No. 1, 19.10.1998, p. 57-65.

Research output: Contribution to journalArticle

Zouridakis, G, Simos, PG, Breier, JI & Papanicolaou, A 1998, 'Functional hemispheric asymmetry assessment in a visual language task using MEG', Brain Topography, vol. 11, no. 1, pp. 57-65. https://doi.org/10.1023/A:1022270620396
Zouridakis, George ; Simos, Panagiotis G. ; Breier, Joshua I. ; Papanicolaou, Andrew. / Functional hemispheric asymmetry assessment in a visual language task using MEG. In: Brain Topography. 1998 ; Vol. 11, No. 1. pp. 57-65.
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