Gastrointestinal and Hepatic Disease in the Inflammatory Myopathies

Chiranjeevi Gadiparthi, Amneet Hans, Kyle Potts, Mohammad Ismail

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Although muscle weakness is the pathognomonic feature of idiopathic inflammatory myopathies, systemic organ involvement is not uncommon. The gastrointestinal and hepatic manifestations are well known. Oropharyngeal dysphagia is the most common gastrointestinal symptom and can be severe. Gastric and small intestinal motility disorders, including chronic intestinal pseudo-obstruction, celiac disease, and inflammatory bowel disease have been described. Comprehensive cancer screening is warranted soon after the diagnosis of inflammatory myopathies due to high risk of occult malignancies. Elevated aminotransferases may suggest muscular injury rather than hepatic dysfunction. Knowledge regarding systemic involvement of inflammatory myopathies can assist in timely diagnosis of these complex disorders.

Original languageEnglish (US)
Pages (from-to)113-129
Number of pages17
JournalRheumatic Disease Clinics of North America
Volume44
Issue number1
DOIs
StatePublished - Feb 1 2018

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Myositis
Gastrointestinal Diseases
Liver
Intestinal Pseudo-Obstruction
Gastrointestinal Motility
Muscle Weakness
Celiac Disease
Deglutition Disorders
Transaminases
Inflammatory Bowel Diseases
Early Detection of Cancer
Stomach
Wounds and Injuries
Neoplasms

All Science Journal Classification (ASJC) codes

  • Rheumatology

Cite this

Gastrointestinal and Hepatic Disease in the Inflammatory Myopathies. / Gadiparthi, Chiranjeevi; Hans, Amneet; Potts, Kyle; Ismail, Mohammad.

In: Rheumatic Disease Clinics of North America, Vol. 44, No. 1, 01.02.2018, p. 113-129.

Research output: Contribution to journalReview article

Gadiparthi, Chiranjeevi ; Hans, Amneet ; Potts, Kyle ; Ismail, Mohammad. / Gastrointestinal and Hepatic Disease in the Inflammatory Myopathies. In: Rheumatic Disease Clinics of North America. 2018 ; Vol. 44, No. 1. pp. 113-129.
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