Gastrointestinal manifestations of AIDS in children

J. O. Haller, Harris Cohen

Research output: Contribution to journalReview article

19 Citations (Scopus)

Abstract

The gastrointestinal manifestations of AIDS in children are related to opportunistic infections, lymphoproliferative disease, and cancer. The infections that affect the gastrointestinal tract at different sites also occur in patients without AIDS. However, in children with AIDS, the infections are more severe, often relapse, and are harder to eradicate. Candidiasis is the most common infection in the esophagus, but infections caused by herpes simplex virus and cytomegalovirus also are common. Radiologic findings include ulcerations, a cobblestone appearance, and disordered motility. Gastritis and enteritis are usually caused by cytomegalovirus. Lesions produced by this virus include ulcerations caused by ischemic necrosis as a result of vasculitis. Barium studies show increased nodularity and effacement of mucosa. Other organisms (typically found in all immunocompromised patients) include Mycobacterium avium-intracellulare, Mycobacterium tuberculosis, Campylobacter, Giardia, and Cryptosporidium. Colitis and proctitis are caused by many of the same enteric pathogens. Cytomegalovirus is the most virulent, causing necrosis, perforation, and often death. Lymphoma, smooth muscle tumors, and Kaposi's sarcoma are the most common neoplasms encountered in children with AIDS.

Original languageEnglish (US)
Pages (from-to)387-393
Number of pages7
JournalAmerican Journal of Roentgenology
Volume162
Issue number2
DOIs
StatePublished - Jan 1 1994
Externally publishedYes

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Acquired Immunodeficiency Syndrome
Cytomegalovirus
Infection
Necrosis
Smooth Muscle Tumor
Proctitis
Giardia
Mycobacterium avium Complex
Cryptosporidium
Campylobacter
Enteritis
Candidiasis
Kaposi's Sarcoma
Opportunistic Infections
Immunocompromised Host
Gastritis
Simplexvirus
Barium
Colitis
Vasculitis

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Gastrointestinal manifestations of AIDS in children. / Haller, J. O.; Cohen, Harris.

In: American Journal of Roentgenology, Vol. 162, No. 2, 01.01.1994, p. 387-393.

Research output: Contribution to journalReview article

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