Gene therapy for ovarian cancer

Kristopher Kimball, T. Michael Numnum, Rodney P. Rocconi, Ronald D. Alvarez

Research output: Contribution to journalReview article

17 Citations (Scopus)

Abstract

Ovarian cancer remains the leading cause of death due to gynecologic cancer in women in the United States. Gene and viral-based therapies represent novel therapeutic approaches for cancer. The manipulation of genetic content of tumor cells toward a therapeutic end has been divided into several general strategies, including molecular chemotherapy, mutation compensation, immunopotentiation, and virotherapy. Improvements in delivery vehicles and in evaluation of gene transfer and viral replication remain important areas of investigation. We highlight the most recent advances in these novel therapeutic approaches for ovarian cancer and include a summary of recent clinical trials.

Original languageEnglish (US)
Pages (from-to)441-447
Number of pages7
JournalCurrent Oncology Reports
Volume8
Issue number6
DOIs
StatePublished - Nov 1 2006
Externally publishedYes

Fingerprint

Genetic Therapy
Ovarian Neoplasms
Viral Genes
Neoplasms
Therapeutics
Cause of Death
Clinical Trials
Drug Therapy
Mutation

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kimball, K., Numnum, T. M., Rocconi, R. P., & Alvarez, R. D. (2006). Gene therapy for ovarian cancer. Current Oncology Reports, 8(6), 441-447. https://doi.org/10.1007/s11912-006-0073-x

Gene therapy for ovarian cancer. / Kimball, Kristopher; Numnum, T. Michael; Rocconi, Rodney P.; Alvarez, Ronald D.

In: Current Oncology Reports, Vol. 8, No. 6, 01.11.2006, p. 441-447.

Research output: Contribution to journalReview article

Kimball, K, Numnum, TM, Rocconi, RP & Alvarez, RD 2006, 'Gene therapy for ovarian cancer', Current Oncology Reports, vol. 8, no. 6, pp. 441-447. https://doi.org/10.1007/s11912-006-0073-x
Kimball, Kristopher ; Numnum, T. Michael ; Rocconi, Rodney P. ; Alvarez, Ronald D. / Gene therapy for ovarian cancer. In: Current Oncology Reports. 2006 ; Vol. 8, No. 6. pp. 441-447.
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