Genetic and Molecular Network Analysis of Behavior

Research output: Chapter in Book/Report/Conference proceedingChapter

14 Citations (Scopus)

Abstract

This chapter provides an introduction into the genetic control and analysis of behavioral variation using powerful online resources. We introduce you to the new field of systems genetics using "case studies" drawn from the world of behavioral genetics that exploit populations of genetically diverse lines of mice. These lines differ very widely in patterns of gene and protein expression in the brain and in patterns of behavior. In this chapter, we address the following set of related questions: (1) Can we combine massive genomic data sets with large aggregates of precise quantitative data on behavior? (2) Can we map causal relations between gene variants and behavioral differences? (3) Can we simultaneously use these highly coherent data sets to understand more about the underlying molecular and cellular basis of behavior?

Original languageEnglish (US)
Title of host publicationInternational Review of Neurobiology
PublisherAcademic Press Inc.
Pages135-157
Number of pages23
DOIs
StatePublished - Jan 1 2012

Publication series

NameInternational Review of Neurobiology
Volume104
ISSN (Print)0074-7742

Fingerprint

Molecular Biology
Behavioral Genetics
Gene Expression
Brain
Population
Genes
Proteins
Datasets

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Cellular and Molecular Neuroscience

Cite this

Williams, R., & Mulligan, M. (2012). Genetic and Molecular Network Analysis of Behavior. In International Review of Neurobiology (pp. 135-157). (International Review of Neurobiology; Vol. 104). Academic Press Inc.. https://doi.org/10.1016/B978-0-12-398323-7.00006-9

Genetic and Molecular Network Analysis of Behavior. / Williams, Robert; Mulligan, Megan.

International Review of Neurobiology. Academic Press Inc., 2012. p. 135-157 (International Review of Neurobiology; Vol. 104).

Research output: Chapter in Book/Report/Conference proceedingChapter

Williams, R & Mulligan, M 2012, Genetic and Molecular Network Analysis of Behavior. in International Review of Neurobiology. International Review of Neurobiology, vol. 104, Academic Press Inc., pp. 135-157. https://doi.org/10.1016/B978-0-12-398323-7.00006-9
Williams R, Mulligan M. Genetic and Molecular Network Analysis of Behavior. In International Review of Neurobiology. Academic Press Inc. 2012. p. 135-157. (International Review of Neurobiology). https://doi.org/10.1016/B978-0-12-398323-7.00006-9
Williams, Robert ; Mulligan, Megan. / Genetic and Molecular Network Analysis of Behavior. International Review of Neurobiology. Academic Press Inc., 2012. pp. 135-157 (International Review of Neurobiology).
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