Genetic variations in vesicoureteral Reflux sequelae

David Hains, Andrew L. Schwaderer

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Urinary tract infections (UTI) are a common condition in children. Vesicoureteral reflux (VUR) represents a common associated condition with childhood UTI. UTI susceptibility appears to have a genetic component based on family and UTI cohort studies. Targeted analysis of innate immune system genetic variations indicate that these variations are important in UTI susceptibility. In this overview, we discuss how current cohorts and genetic strategies can be implemented to discover new susceptibility loci in patients with UTI.

Original languageEnglish (US)
Article number14
JournalPathogens
Volume5
Issue number1
DOIs
StatePublished - Mar 1 2016

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Vesico-Ureteral Reflux
Urinary Tract Infections
Immune System
Cohort Studies

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Molecular Biology
  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Genetic variations in vesicoureteral Reflux sequelae. / Hains, David; Schwaderer, Andrew L.

In: Pathogens, Vol. 5, No. 1, 14, 01.03.2016.

Research output: Contribution to journalReview article

Hains, David ; Schwaderer, Andrew L. / Genetic variations in vesicoureteral Reflux sequelae. In: Pathogens. 2016 ; Vol. 5, No. 1.
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