Granulomatous angiitis masquerading as a mass lesion. Magnetic resonance imaging and stereotactic biopsy findings in a patient with occult Hodgkin's disease

Mahlon Johnson, Robert Maciunas, Philip Dutt, Mary Ellen Clinton, Robert Collins

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Granulomatous angiitis is a frequently fatal central nervous system vasculitis of unknown pathogenesis sporadically associated with Hodgkin's disease, mixed cellularity type. We describe a 58-year-old woman presenting with headaches, progressive spastic paraparesis, equivocal computed tomography findings, and magnetic resonance imaging findings of increased signal intensity biparietally on T2-weighted imaging in à relatively discrete pattern. Magnetic resonance imaging-directed serial stereotactic biopsies revealed granulomatous angiitis throughout the right parieto-occipital region and splenium. Simultaneous biopsy of an enlarged submandibular mass revealed Hodgkin's disease, lymphocyte-predominant type. This case shows that granulomatous angiitis may be associated with magnetic resonance imaging findings suggesting a mass lesion in lymphoctye-predominant as well as mixed cellularity Hodgkin's disease.

Original languageEnglish (US)
Pages (from-to)49-53
Number of pages5
JournalSurgical Neurology
Volume31
Issue number1
DOIs
StatePublished - Jan 1 1989
Externally publishedYes

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Central Nervous System Vasculitis
Hodgkin Disease
Magnetic Resonance Imaging
Biopsy
Spastic Paraparesis
Occipital Lobe
Headache
Tomography
Lymphocytes

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

Cite this

Granulomatous angiitis masquerading as a mass lesion. Magnetic resonance imaging and stereotactic biopsy findings in a patient with occult Hodgkin's disease. / Johnson, Mahlon; Maciunas, Robert; Dutt, Philip; Clinton, Mary Ellen; Collins, Robert.

In: Surgical Neurology, Vol. 31, No. 1, 01.01.1989, p. 49-53.

Research output: Contribution to journalArticle

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