Group A streptococcal vaccines

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The pathogenesis of group A streptococcal infections, and antigens that contribute to protective immune responses are reviewed. Several approaches to vaccine development are discussed. Data are provided from preclinical studies of multivalent M protein-based vaccines that evoke protective antibodies in laboratory animals. Also discussed are future strategies for the development of broadly protective vaccines, and their potential impact on the incidence of streptococcal infections, and acute rheumatic fever.

Original languageEnglish (US)
Pages (from-to)227-243
Number of pages17
JournalInfectious Disease Clinics of North America
Volume13
Issue number1
DOIs
StatePublished - Jan 1 1999
Externally publishedYes

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Streptococcal Vaccines
Streptococcal Infections
Vaccines
Rheumatic Fever
Laboratory Animals
Antigens
Antibodies
Incidence
Proteins

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Group A streptococcal vaccines. / Dale, James.

In: Infectious Disease Clinics of North America, Vol. 13, No. 1, 01.01.1999, p. 227-243.

Research output: Contribution to journalArticle

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