Heart transplantation in an 8-month-old girl

10th Anniversary report

O. H. Frazier, O. U.J. Okereke, B. Radovancevic, Jeffrey Towbin, J. K. Price, S. Denfield, L. B. Chandler, P. Powers, J. T. Bricker

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

In 1984, Dr. Denton A. Cooley led a surgical team that implanted a cardiac allograft in an 8-month-old girl who had end-stage cardiac disease secondary to endocardial fibroelastosis. At that time, experience with cardiac transplantation in infants was limited, and the long-term effects of the procedure were cause for concern. Ten years later, our patient is a healthy 4th-grade student who enjoys a remarkably normal life. She has grown and developed quite satisfactorily, and her heart has enlarged in proportion to her overall somatic growth. Long-term immunosuppression has produced no adverse effects, and the child's medical problems have differed tittle from those of her peers. This landmark case has yielded preliminary answers to a number of important questions about cardiac transplantation in infants and has confirmed our original opinion that the procedure is weft warranted in selected patients.

Original languageEnglish (US)
Pages (from-to)115-118
Number of pages4
JournalTexas Heart Institute Journal
Volume22
Issue number2
StatePublished - Jan 1 1995
Externally publishedYes

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Anniversaries and Special Events
Heart Transplantation
Endocardial Fibroelastosis
Cardiomegaly
Immunosuppression
Allografts
Heart Diseases
Students
Growth

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Frazier, O. H., Okereke, O. U. J., Radovancevic, B., Towbin, J., Price, J. K., Denfield, S., ... Bricker, J. T. (1995). Heart transplantation in an 8-month-old girl: 10th Anniversary report. Texas Heart Institute Journal, 22(2), 115-118.

Heart transplantation in an 8-month-old girl : 10th Anniversary report. / Frazier, O. H.; Okereke, O. U.J.; Radovancevic, B.; Towbin, Jeffrey; Price, J. K.; Denfield, S.; Chandler, L. B.; Powers, P.; Bricker, J. T.

In: Texas Heart Institute Journal, Vol. 22, No. 2, 01.01.1995, p. 115-118.

Research output: Contribution to journalArticle

Frazier, OH, Okereke, OUJ, Radovancevic, B, Towbin, J, Price, JK, Denfield, S, Chandler, LB, Powers, P & Bricker, JT 1995, 'Heart transplantation in an 8-month-old girl: 10th Anniversary report', Texas Heart Institute Journal, vol. 22, no. 2, pp. 115-118.
Frazier OH, Okereke OUJ, Radovancevic B, Towbin J, Price JK, Denfield S et al. Heart transplantation in an 8-month-old girl: 10th Anniversary report. Texas Heart Institute Journal. 1995 Jan 1;22(2):115-118.
Frazier, O. H. ; Okereke, O. U.J. ; Radovancevic, B. ; Towbin, Jeffrey ; Price, J. K. ; Denfield, S. ; Chandler, L. B. ; Powers, P. ; Bricker, J. T. / Heart transplantation in an 8-month-old girl : 10th Anniversary report. In: Texas Heart Institute Journal. 1995 ; Vol. 22, No. 2. pp. 115-118.
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