Hepatobiliary abnormalities associated with postanginal sepsis. Common manifestations of an uncommon disease

Larry M. Baddour, Mack Land, Fred F. Barrett, Fred P. Rivara, William M. Bruce, Alan L. Bisno

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

We describe eight patients with postanginal sepsis, a rare, potentially life-threatening complication of oropharyngeal infection. Six of the patients manifested jaundice, hepatomegaly, and liver function abnormalities, and in several this led to an erroneous suspicion of primary hepatobiliary disease. All eight patients survived the infection, although many suffered local or disseminated septic complications and required prolonged hospitalization. The pathophysiologic mechanisms responsible for hepatotoxicity in patients with postanginal sepsis are not understood. Physicians must be cognizant, however, of the frequent occurrence of jaundice in septicemic anaerobic processes, and this finding should not obscure the existence of post-anginal parapharyngeal and jugular venous infection.

Original languageEnglish (US)
Pages (from-to)19-28
Number of pages10
JournalDiagnostic Microbiology and Infectious Disease
Volume4
Issue number1
DOIs
StatePublished - Jan 1 1986
Externally publishedYes

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Lemierre Syndrome
Jaundice
Infection
Hepatomegaly
Hospitalization
Neck
Physicians
Liver

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Hepatobiliary abnormalities associated with postanginal sepsis. Common manifestations of an uncommon disease. / Baddour, Larry M.; Land, Mack; Barrett, Fred F.; Rivara, Fred P.; Bruce, William M.; Bisno, Alan L.

In: Diagnostic Microbiology and Infectious Disease, Vol. 4, No. 1, 01.01.1986, p. 19-28.

Research output: Contribution to journalArticle

Baddour, Larry M. ; Land, Mack ; Barrett, Fred F. ; Rivara, Fred P. ; Bruce, William M. ; Bisno, Alan L. / Hepatobiliary abnormalities associated with postanginal sepsis. Common manifestations of an uncommon disease. In: Diagnostic Microbiology and Infectious Disease. 1986 ; Vol. 4, No. 1. pp. 19-28.
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