Hepatoblastoma and abernethy malformation type I

Case report

Catalina Correa, Juan P. Luengas, Scott Howard, Galo Veintemilla

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 2-year-old boy presented with pneumonia and an abdominal mass was noted incidentally. A right lobe hepatic mass classified as PRETEXT III and congenital absence of the portal vein with drainage of the superior mesenteric vein to the inferior vena cava (Abernethy malformation type I) were confirmed by computed tomography and angiography. After a clinical diagnosis of hepatoblastoma had been made, he was treated with 4 cycles of doxorubicin and cisplatin and hepatic arterial chemoembolization with doxorubicin, after which the tumor was classified as POSTEXT III. He underwent a right extended hepatic lobectomy with resection of the caudate lobe but died on postoperative day 4 due to hepatic failure. The Abernethy malformation type I is associated with the development of hepatic tumors, and the abnormal blood flow might predispose to hepatic failure after liver resection. Extensive study of the hepatic vasculature is warranted in patients with suspected malformations. Liver transplant could be considered in patients with congenital portosystemic shunt and malignant liver tumors.

Original languageEnglish (US)
Pages (from-to)e79-e81
JournalJournal of Pediatric Hematology/Oncology
Volume39
Issue number2
DOIs
StatePublished - Jan 1 2017
Externally publishedYes

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Hepatoblastoma
Liver
Liver Failure
Doxorubicin
Surgical Portasystemic Shunt
Mesenteric Veins
Neoplasms
Inferior Vena Cava
Portal Vein
Cisplatin
Drainage
Pneumonia
Transplants

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

Cite this

Hepatoblastoma and abernethy malformation type I : Case report. / Correa, Catalina; Luengas, Juan P.; Howard, Scott; Veintemilla, Galo.

In: Journal of Pediatric Hematology/Oncology, Vol. 39, No. 2, 01.01.2017, p. e79-e81.

Research output: Contribution to journalArticle

Correa, Catalina ; Luengas, Juan P. ; Howard, Scott ; Veintemilla, Galo. / Hepatoblastoma and abernethy malformation type I : Case report. In: Journal of Pediatric Hematology/Oncology. 2017 ; Vol. 39, No. 2. pp. e79-e81.
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