Hepatoblastoma and prune belly syndrome

A potential association

Brian Becknell, Priya Pais, Grace Onimoe, Hemalatha Rangarajan, Andrew L. Schwaderer, Kirk McHugh, Mark A. Ranalli, David Hains

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Prune belly syndrome (PBS) is a congenital anomaly characterized by the clinical triad of lax abdominal musculature, bilateral cryptorchidism, and abnormalities of the kidney and urinary tract. Previous reports of malignancy in patients with PBS have been limited to germ cell tumors. Hepatoblastoma (HBL) is the most common hepatic malignancy of childhood, affecting approximately 100 children each year in the USA. We describe a set of 4 pediatric patients with PBS and HBL. All individuals were born after 2002. These subjects lacked genetic, natal, or environmental factors known to confer risk of HBL. The occurrence of PBS and HBL in these patients constitutes a novel potential association.

Original languageEnglish (US)
Pages (from-to)1269-1273
Number of pages5
JournalPediatric Nephrology
Volume26
Issue number8
DOIs
StatePublished - Aug 1 2011

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Prune Belly Syndrome
Hepatoblastoma
Cryptorchidism
Germ Cell and Embryonal Neoplasms
Urinary Tract
Neoplasms
Pediatrics
Kidney
Liver

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Nephrology

Cite this

Becknell, B., Pais, P., Onimoe, G., Rangarajan, H., Schwaderer, A. L., McHugh, K., ... Hains, D. (2011). Hepatoblastoma and prune belly syndrome: A potential association. Pediatric Nephrology, 26(8), 1269-1273. https://doi.org/10.1007/s00467-011-1874-1

Hepatoblastoma and prune belly syndrome : A potential association. / Becknell, Brian; Pais, Priya; Onimoe, Grace; Rangarajan, Hemalatha; Schwaderer, Andrew L.; McHugh, Kirk; Ranalli, Mark A.; Hains, David.

In: Pediatric Nephrology, Vol. 26, No. 8, 01.08.2011, p. 1269-1273.

Research output: Contribution to journalArticle

Becknell, B, Pais, P, Onimoe, G, Rangarajan, H, Schwaderer, AL, McHugh, K, Ranalli, MA & Hains, D 2011, 'Hepatoblastoma and prune belly syndrome: A potential association', Pediatric Nephrology, vol. 26, no. 8, pp. 1269-1273. https://doi.org/10.1007/s00467-011-1874-1
Becknell B, Pais P, Onimoe G, Rangarajan H, Schwaderer AL, McHugh K et al. Hepatoblastoma and prune belly syndrome: A potential association. Pediatric Nephrology. 2011 Aug 1;26(8):1269-1273. https://doi.org/10.1007/s00467-011-1874-1
Becknell, Brian ; Pais, Priya ; Onimoe, Grace ; Rangarajan, Hemalatha ; Schwaderer, Andrew L. ; McHugh, Kirk ; Ranalli, Mark A. ; Hains, David. / Hepatoblastoma and prune belly syndrome : A potential association. In: Pediatric Nephrology. 2011 ; Vol. 26, No. 8. pp. 1269-1273.
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