Hepatocellular carcinoma

resection with adjuvant hepatic artery infusion therapy vs resection alone. A systematic review and meta-analysis

Alexandra Moran, Lorena Flor Ramos, Omar Picado, Fiorella Pendola, Danny Sleeman, Vikas Dudeja, Nipun Merchant, Danny Yakoub

Research output: Contribution to journalReview article

Abstract

Hepatocellular carcinoma (HCC) has a recurrence rate of up to 70% in 5 years after resection, detrimentally lowering survival. The role of adjuvant therapy remains controversial; therefore, the aim of this study was to evaluate the disease-free and overall survival of patients with HCC, not candidates for transplantation, undergoing resection and adjuvant hepatic artery infusion therapy vs resection alone. Our meta-analysis showed that adjuvant HAIC improves overall and disease-free survival after resection, especially in tumors ≥7 cm.

Original languageEnglish (US)
Pages (from-to)455-463
Number of pages9
JournalJournal of Surgical Oncology
Volume119
Issue number4
DOIs
StatePublished - Mar 15 2019

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Hepatic Artery
Disease-Free Survival
Meta-Analysis
Hepatocellular Carcinoma
Transplantation
Recurrence
Survival
Therapeutics
Neoplasms

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oncology

Cite this

Hepatocellular carcinoma : resection with adjuvant hepatic artery infusion therapy vs resection alone. A systematic review and meta-analysis. / Moran, Alexandra; Ramos, Lorena Flor; Picado, Omar; Pendola, Fiorella; Sleeman, Danny; Dudeja, Vikas; Merchant, Nipun; Yakoub, Danny.

In: Journal of Surgical Oncology, Vol. 119, No. 4, 15.03.2019, p. 455-463.

Research output: Contribution to journalReview article

Moran, Alexandra ; Ramos, Lorena Flor ; Picado, Omar ; Pendola, Fiorella ; Sleeman, Danny ; Dudeja, Vikas ; Merchant, Nipun ; Yakoub, Danny. / Hepatocellular carcinoma : resection with adjuvant hepatic artery infusion therapy vs resection alone. A systematic review and meta-analysis. In: Journal of Surgical Oncology. 2019 ; Vol. 119, No. 4. pp. 455-463.
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AU - Dudeja, Vikas

AU - Merchant, Nipun

AU - Yakoub, Danny

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