High-sensitivity C-reactive protein in stroke patients – The importance in consideration of influence of multiple factors in the predictability for disease severity and death

Hong Yu, Yue Huang, Xin Yu Chen, Wen Bao Nie, Yong Jun Wang, Yan Jiao, Guy Reed, Weikuan Gu, Hong Chen

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

High sensitivity C-reactive protein (hsCRP) has been evaluated as a biomarker in stroke and relevant pathological diseases. While its predictive values in several pathological phenotypes have been confirmed, controversy exists among different studies. This review summarizes reports of the predictive values of hsCRP for the diagnosis, etiology, prognosis and mortality of stroke diseases. The current literature suggests that CRP expression is influenced by multiple factors, such as polymorphisms, the genomic backgrounds and gender. However, few reported studies analyzed data based on all these multiple factors. Future studies should focus on comprehensive analysis based on multiple factors.

Original languageEnglish (US)
Pages (from-to)12-19
Number of pages8
JournalJournal of Clinical Neuroscience
Volume36
DOIs
StatePublished - Feb 1 2017

Fingerprint

C-Reactive Protein
Stroke
Biomarkers
Phenotype
Mortality

All Science Journal Classification (ASJC) codes

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

Cite this

High-sensitivity C-reactive protein in stroke patients – The importance in consideration of influence of multiple factors in the predictability for disease severity and death. / Yu, Hong; Huang, Yue; Chen, Xin Yu; Nie, Wen Bao; Wang, Yong Jun; Jiao, Yan; Reed, Guy; Gu, Weikuan; Chen, Hong.

In: Journal of Clinical Neuroscience, Vol. 36, 01.02.2017, p. 12-19.

Research output: Contribution to journalReview article

@article{82e3154f824e422aaf79b464e12ae0d9,
title = "High-sensitivity C-reactive protein in stroke patients – The importance in consideration of influence of multiple factors in the predictability for disease severity and death",
abstract = "High sensitivity C-reactive protein (hsCRP) has been evaluated as a biomarker in stroke and relevant pathological diseases. While its predictive values in several pathological phenotypes have been confirmed, controversy exists among different studies. This review summarizes reports of the predictive values of hsCRP for the diagnosis, etiology, prognosis and mortality of stroke diseases. The current literature suggests that CRP expression is influenced by multiple factors, such as polymorphisms, the genomic backgrounds and gender. However, few reported studies analyzed data based on all these multiple factors. Future studies should focus on comprehensive analysis based on multiple factors.",
author = "Hong Yu and Yue Huang and Chen, {Xin Yu} and Nie, {Wen Bao} and Wang, {Yong Jun} and Yan Jiao and Guy Reed and Weikuan Gu and Hong Chen",
year = "2017",
month = "2",
day = "1",
doi = "10.1016/j.jocn.2016.10.020",
language = "English (US)",
volume = "36",
pages = "12--19",
journal = "Journal of Clinical Neuroscience",
issn = "0967-5868",
publisher = "Churchill Livingstone",

}

TY - JOUR

T1 - High-sensitivity C-reactive protein in stroke patients – The importance in consideration of influence of multiple factors in the predictability for disease severity and death

AU - Yu, Hong

AU - Huang, Yue

AU - Chen, Xin Yu

AU - Nie, Wen Bao

AU - Wang, Yong Jun

AU - Jiao, Yan

AU - Reed, Guy

AU - Gu, Weikuan

AU - Chen, Hong

PY - 2017/2/1

Y1 - 2017/2/1

N2 - High sensitivity C-reactive protein (hsCRP) has been evaluated as a biomarker in stroke and relevant pathological diseases. While its predictive values in several pathological phenotypes have been confirmed, controversy exists among different studies. This review summarizes reports of the predictive values of hsCRP for the diagnosis, etiology, prognosis and mortality of stroke diseases. The current literature suggests that CRP expression is influenced by multiple factors, such as polymorphisms, the genomic backgrounds and gender. However, few reported studies analyzed data based on all these multiple factors. Future studies should focus on comprehensive analysis based on multiple factors.

AB - High sensitivity C-reactive protein (hsCRP) has been evaluated as a biomarker in stroke and relevant pathological diseases. While its predictive values in several pathological phenotypes have been confirmed, controversy exists among different studies. This review summarizes reports of the predictive values of hsCRP for the diagnosis, etiology, prognosis and mortality of stroke diseases. The current literature suggests that CRP expression is influenced by multiple factors, such as polymorphisms, the genomic backgrounds and gender. However, few reported studies analyzed data based on all these multiple factors. Future studies should focus on comprehensive analysis based on multiple factors.

UR - http://www.scopus.com/inward/record.url?scp=85006137602&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85006137602&partnerID=8YFLogxK

U2 - 10.1016/j.jocn.2016.10.020

DO - 10.1016/j.jocn.2016.10.020

M3 - Review article

VL - 36

SP - 12

EP - 19

JO - Journal of Clinical Neuroscience

JF - Journal of Clinical Neuroscience

SN - 0967-5868

ER -