High speed photographic analysis of aerosols produced by metered dose inhalers

Rajiv Dhand, S. K. MALIK, M. BALAKRISHNAN, S. R. VERMA

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Abstract— The design of pressurized metered dose inhalers (MDI) used to assess asthma is variable. We have examined the aerosol spray flumes generated by four commercially available MDI products using high speed video photography. For this purpose a moulded jacket was designed which could hold the inhaler in an immovable position during actuation. Fresh inhalers were fitted in the jacket after thorough shaking and three successive actuations 30 s apart were filmed with a high speed video camera (200 frames s−1). The aerosol, ejected at high velocity into calm room air, was seen to have a ‘jet’ phase followed by a ‘cloud’ phase as a result of particle dispersion. Filming was continued till the flume could no longer be visualized on the TV monitor. High speed photography was used to record flumes seen on the video monitor, to enable characterization of flume appearance, dimensions and mean velocity. 1988 Royal Pharmaceutical Society of Great Britain

Original languageEnglish (US)
Pages (from-to)429-430
Number of pages2
JournalJournal of Pharmacy and Pharmacology
Volume40
Issue number6
DOIs
StatePublished - Jan 1 1988

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Metered Dose Inhalers
Nebulizers and Vaporizers
Photography
Aerosols
Asthma
Air

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science

Cite this

High speed photographic analysis of aerosols produced by metered dose inhalers. / Dhand, Rajiv; MALIK, S. K.; BALAKRISHNAN, M.; VERMA, S. R.

In: Journal of Pharmacy and Pharmacology, Vol. 40, No. 6, 01.01.1988, p. 429-430.

Research output: Contribution to journalArticle

Dhand, Rajiv ; MALIK, S. K. ; BALAKRISHNAN, M. ; VERMA, S. R. / High speed photographic analysis of aerosols produced by metered dose inhalers. In: Journal of Pharmacy and Pharmacology. 1988 ; Vol. 40, No. 6. pp. 429-430.
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