Histoplasma panniculitis in dermatomyositis

Juan P. Frias, Joseph W. Huston, Paul C. McNabb

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

This report describes the coexistence of infectious panniculitis due to Histoplasma capsulatum in three patients with dermatomyositis. In each case, the appearance of panniculitis was the predominant clinical manifestation of histoplasmosis. Oral ulcers, lymphadenopathy, pulmonary infiltrates, hepatosplenomegaly, and other cardinal features of disseminated histoplasmosis were notably absent. The clinical presentation of panniculitis may initially be interpreted as worsening of dermatomyositis and can lead to delay in diagnosis and institution of antifungal therapy. Histoplasmosis should be placed high on the differential diagnosis whenever symptomatic panniculitis is observed in the setting of myositis. Clinicians should not be reluctant to perform full thickness biopsies in patients with panniculitis who are on immunosuppressive therapies. Antifungal therapy and reduction in corticosteroids resulted in excellent clinical response with no relapse of infection in this small series.

Original languageEnglish (US)
Pages (from-to)353-357
Number of pages5
JournalJournal of Clinical Rheumatology
Volume3
Issue number6
StatePublished - Dec 1997
Externally publishedYes

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Panniculitis
Histoplasma
Dermatomyositis
Histoplasmosis
Oral Ulcer
Myositis
Immunosuppressive Agents
Adrenal Cortex Hormones
Differential Diagnosis
Therapeutics
Biopsy
Recurrence
Lung
Infection

All Science Journal Classification (ASJC) codes

  • Rheumatology

Cite this

Frias, J. P., Huston, J. W., & McNabb, P. C. (1997). Histoplasma panniculitis in dermatomyositis. Journal of Clinical Rheumatology, 3(6), 353-357.

Histoplasma panniculitis in dermatomyositis. / Frias, Juan P.; Huston, Joseph W.; McNabb, Paul C.

In: Journal of Clinical Rheumatology, Vol. 3, No. 6, 12.1997, p. 353-357.

Research output: Contribution to journalArticle

Frias, JP, Huston, JW & McNabb, PC 1997, 'Histoplasma panniculitis in dermatomyositis', Journal of Clinical Rheumatology, vol. 3, no. 6, pp. 353-357.
Frias JP, Huston JW, McNabb PC. Histoplasma panniculitis in dermatomyositis. Journal of Clinical Rheumatology. 1997 Dec;3(6):353-357.
Frias, Juan P. ; Huston, Joseph W. ; McNabb, Paul C. / Histoplasma panniculitis in dermatomyositis. In: Journal of Clinical Rheumatology. 1997 ; Vol. 3, No. 6. pp. 353-357.
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