How center volumes affect early outcomes in acute myeloid leukemia

Andrew W. Hahn, Omer Jamy, Sara Nunnery, George Yaghmour, Smith Giri, Ranjan Pathak, Michael Martin

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Early mortality (EM) is all too frequent during induction chemotherapy for acute myeloid leukemia. Older patients shoulder an undue amount of this burden as a result of the inherent biology of their disease and increased comorbidities. EM rates in academic centers have seen a sharp decline over the past 20 years; however, data from population-based registries show that EM rates for the general population have significantly lagged behind. In this review, we analyze the data available on EM in academic centers and the general population, explore recent improvements in supportive care and the use of predictive models, and finally investigate the relationship between case volume and complications during chemotherapy.

Original languageEnglish (US)
Pages (from-to)646-654
Number of pages9
JournalClinical Lymphoma, Myeloma and Leukemia
Volume15
Issue number11
DOIs
StatePublished - Jan 1 2015

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Acute Myeloid Leukemia
Mortality
Population
Induction Chemotherapy
Registries
Comorbidity
Drug Therapy

All Science Journal Classification (ASJC) codes

  • Hematology
  • Oncology
  • Cancer Research

Cite this

How center volumes affect early outcomes in acute myeloid leukemia. / Hahn, Andrew W.; Jamy, Omer; Nunnery, Sara; Yaghmour, George; Giri, Smith; Pathak, Ranjan; Martin, Michael.

In: Clinical Lymphoma, Myeloma and Leukemia, Vol. 15, No. 11, 01.01.2015, p. 646-654.

Research output: Contribution to journalReview article

Hahn, Andrew W. ; Jamy, Omer ; Nunnery, Sara ; Yaghmour, George ; Giri, Smith ; Pathak, Ranjan ; Martin, Michael. / How center volumes affect early outcomes in acute myeloid leukemia. In: Clinical Lymphoma, Myeloma and Leukemia. 2015 ; Vol. 15, No. 11. pp. 646-654.
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